Sluis-Cremer N - Search Results

1

Relationship between enzyme activity and dimeric structure of recombinant HIV-1 reverse transcriptase.

Tachedjian G, Radzio J, Sluis-Cremer N. Tachedjian G, et al. Proteins. 2005 Jul 1;60(1):5-13. doi: 10.1002/prot.20480. Proteins. 2005. PMID: 15852304

2

Modulation of the oligomeric structures of HIV-1 retroviral enzymes by synthetic peptides and small molecules.

Sluis-Cremer N, Tachedjian G. Sluis-Cremer N, et al. Eur J Biochem. 2002 Nov;269(21):5103-11. doi: 10.1046/j.1432-1033.2002.03216.x. Eur J Biochem. 2002. PMID: 12392542 Free article. Review.

3

Structure-activity relationships in HIV-1 reverse transcriptase revealed by radiation target analysis.

Sluis-Cremer N, Kempner E, Parniak MA. Sluis-Cremer N, et al. Protein Sci. 2003 Sep;12(9):2081-6. doi: 10.1110/ps.03130503. Protein Sci. 2003. PMID: 12931006 Free PMC article.

4

Efavirenz enhances the proteolytic processing of an HIV-1 pol polyprotein precursor and reverse transcriptase homodimer formation.

Tachedjian G, Moore KL, Goff SP, Sluis-Cremer N. Tachedjian G, et al. FEBS Lett. 2005 Jan 17;579(2):379-84. doi: 10.1016/j.febslet.2004.11.099. FEBS Lett. 2005. PMID: 15642347 Free article.

5

Stereo-selectivity of HIV-1 reverse transcriptase toward isomers of thymidine-5'-O-1-thiotriphosphate.

Radzio J, Sluis-Cremer N. Radzio J, et al. Protein Sci. 2005 Jul;14(7):1929-33. doi: 10.1110/ps.051445605. Epub 2005 Jun 3. Protein Sci. 2005. PMID: 15937285 Free PMC article.

6

Dimerization of human immunodeficiency virus type 1 reverse transcriptase as an antiviral target.

Srivastava S, Sluis-Cremer N, Tachedjian G. Srivastava S, et al. Curr Pharm Des. 2006;12(15):1879-94. doi: 10.2174/138161206776873590. Curr Pharm Des. 2006. PMID: 16724954 Review.

7

Potent nonnucleoside reverse transcriptase inhibitors target HIV-1 Gag-Pol.

Figueiredo A, Moore KL, Mak J, Sluis-Cremer N, de Bethune MP, Tachedjian G. Figueiredo A, et al. PLoS Pathog. 2006 Nov;2(11):e119. doi: 10.1371/journal.ppat.0020119. PLoS Pathog. 2006. PMID: 17096588 Free PMC article.

8

Characterization of novel non-nucleoside reverse transcriptase (RT) inhibitor resistance mutations at residues 132 and 135 in the 51 kDa subunit of HIV-1 RT.

Nissley DV, Radzio J, Ambrose Z, Sheen CW, Hamamouch N, Moore KL, Tachedjian G, Sluis-Cremer N. Nissley DV, et al. Biochem J. 2007 May 15;404(1):151-7. doi: 10.1042/BJ20061814. Biochem J. 2007. PMID: 17286555 Free PMC article.

9

Probing nonnucleoside inhibitor-induced active-site distortion in HIV-1 reverse transcriptase by transient kinetic analyses.

Xia Q, Radzio J, Anderson KS, Sluis-Cremer N. Xia Q, et al. Protein Sci. 2007 Aug;16(8):1728-37. doi: 10.1110/ps.072829007. Protein Sci. 2007. PMID: 17656585 Free PMC article.

10

Mechanisms by which the G333D mutation in human immunodeficiency virus type 1 Reverse transcriptase facilitates dual resistance to zidovudine and lamivudine.

Zelina S, Sheen CW, Radzio J, Mellors JW, Sluis-Cremer N. Zelina S, et al. Antimicrob Agents Chemother. 2008 Jan;52(1):157-63. doi: 10.1128/AAC.00904-07. Epub 2007 Oct 29. Antimicrob Agents Chemother. 2008. PMID: 17967907 Free PMC article.

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