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30 results

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Page 1
Synthesis, biological evaluation, and receptor docking simulations of 2-[(acylamino)ethyl]-1,4-benzodiazepines as kappa-opioid receptor agonists endowed with antinociceptive and antiamnesic activity.
Anzini M, Canullo L, Braile C, Cappelli A, Gallelli A, Vomero S, Menziani MC, De Benedetti PG, Rizzo M, Collina S, Azzolina O, Sbacchi M, Ghelardini C, Galeotti N. Anzini M, et al. Among authors: gallelli a. J Med Chem. 2003 Aug 28;46(18):3853-64. doi: 10.1021/jm0307640. J Med Chem. 2003. PMID: 12930147
A non-peptide NK1 receptor agonist showing subpicomolar affinity.
Cappelli A, Giuliani G, Pericot Mohr Gl Gl, Gallelli A, Anzini M, Vomero S, Cupello A, Scarrone S, Matarrese M, Moresco RM, Fazio F, Finetti F, Morbidelli L, Ziche M. Cappelli A, et al. Among authors: gallelli a. J Med Chem. 2004 Mar 11;47(6):1315-8. doi: 10.1021/jm034219a. J Med Chem. 2004. PMID: 14998319
Design, synthesis, structural studies, biological evaluation, and computational simulations of novel potent AT(1) angiotensin II receptor antagonists based on the 4-phenylquinoline structure.
Cappelli A, Pericot Mohr Gl Gl, Gallelli A, Rizzo M, Anzini M, Vomero S, Mennuni L, Ferrari F, Makovec F, Menziani MC, De Benedetti PG, Giorgi G. Cappelli A, et al. Among authors: gallelli a. J Med Chem. 2004 May 6;47(10):2574-86. doi: 10.1021/jm031100t. J Med Chem. 2004. PMID: 15115399
Further studies on the interaction of the 5-hydroxytryptamine3 (5-HT3) receptor with arylpiperazine ligands. development of a new 5-HT3 receptor ligand showing potent acetylcholinesterase inhibitory properties.
Cappelli A, Gallelli A, Manini M, Anzini M, Mennuni L, Makovec F, Menziani MC, Alcaro S, Ortuso F, Vomero S. Cappelli A, et al. Among authors: gallelli a. J Med Chem. 2005 May 19;48(10):3564-75. doi: 10.1021/jm0493461. J Med Chem. 2005. PMID: 15887964
Design, synthesis, and biological evaluation of AT1 angiotensin II receptor antagonists based on the pyrazolo[3,4-b]pyridine and related heteroaromatic bicyclic systems.
Cappelli A, Nannicini C, Gallelli A, Giuliani G, Valenti S, Mohr Gl, Anzini M, Mennuni L, Ferrari F, Caselli G, Giordani A, Peris W, Makovec F, Giorgi G, Vomero S. Cappelli A, et al. Among authors: gallelli a. J Med Chem. 2008 Apr 10;51(7):2137-46. doi: 10.1021/jm7011563. Epub 2008 Mar 5. J Med Chem. 2008. PMID: 18318468
Bivalent Ligands for the Serotonin 5-HT3 Receptor.
Cappelli A, Manini M, Paolino M, Gallelli A, Anzini M, Mennuni L, Del Cadia M, De Rienzo F, Menziani MC, Vomero S. Cappelli A, et al. Among authors: gallelli a. ACS Med Chem Lett. 2011 May 9;2(8):571-6. doi: 10.1021/ml2000388. eCollection 2011 Aug 11. ACS Med Chem Lett. 2011. PMID: 24900351 Free PMC article.
Chiral arylpyrrolidinols: preparation and biological profile.
Collina S, Rossi D, Loddo G, Barbieri A, Lanza E, Linati L, Alcaro S, Gallelli A, Azzolina O. Collina S, et al. Among authors: gallelli a. Bioorg Med Chem. 2005 May 2;13(9):3117-26. doi: 10.1016/j.bmc.2005.02.054. Bioorg Med Chem. 2005. PMID: 15809147
30 results