Setola V - Search Results

1

Molecular determinants for the interaction of the valvulopathic anorexigen norfenfluramine with the 5-HT2B receptor.

Setola V, Dukat M, Glennon RA, Roth BL. Setola V, et al. Mol Pharmacol. 2005 Jul;68(1):20-33. doi: 10.1124/mol.104.009266. Epub 2005 Apr 14. Mol Pharmacol. 2005. PMID: 15831837

2

3,4-methylenedioxymethamphetamine (MDMA, "Ecstasy") induces fenfluramine-like proliferative actions on human cardiac valvular interstitial cells in vitro.

Setola V, Hufeisen SJ, Grande-Allen KJ, Vesely I, Glennon RA, Blough B, Rothman RB, Roth BL. Setola V, et al. Mol Pharmacol. 2003 Jun;63(6):1223-9. doi: 10.1124/mol.63.6.1223. Mol Pharmacol. 2003. PMID: 12761331

3

Why mice are neither miniature humans nor small rats: a cautionary tale involving 5-hydroxytryptamine-6 serotonin receptor species variants.

Setola V, Roth BL. Setola V, et al. Mol Pharmacol. 2003 Dec;64(6):1277-8. doi: 10.1124/mol.64.6.1277. Mol Pharmacol. 2003. PMID: 14645656 Review. No abstract available.

4

Screening the receptorome reveals molecular targets responsible for drug-induced side effects: focus on 'fen-phen'.

Setola V, Roth BL. Setola V, et al. Expert Opin Drug Metab Toxicol. 2005 Oct;1(3):377-87. doi: 10.1517/17425255.1.3.377. Expert Opin Drug Metab Toxicol. 2005. PMID: 16863450 Review.

5

Pharmacologic analysis of non-synonymous coding h5-HT2A SNPs reveals alterations in atypical antipsychotic and agonist efficacies.

Davies MA, Setola V, Strachan RT, Sheffler DJ, Salay E, Hufeisen SJ, Roth BL. Davies MA, et al. Among authors: setola v. Pharmacogenomics J. 2006 Jan-Feb;6(1):42-51. doi: 10.1038/sj.tpj.6500342. Pharmacogenomics J. 2006. PMID: 16314884

6

Parallel functional activity profiling reveals valvulopathogens are potent 5-hydroxytryptamine(2B) receptor agonists: implications for drug safety assessment.

Huang XP, Setola V, Yadav PN, Allen JA, Rogan SC, Hanson BJ, Revankar C, Robers M, Doucette C, Roth BL. Huang XP, et al. Among authors: setola v. Mol Pharmacol. 2009 Oct;76(4):710-22. doi: 10.1124/mol.109.058057. Epub 2009 Jul 1. Mol Pharmacol. 2009. PMID: 19570945 Free PMC article.

7

Serotonin receptors and heart valve disease--it was meant 2B.

Hutcheson JD, Setola V, Roth BL, Merryman WD. Hutcheson JD, et al. Among authors: setola v. Pharmacol Ther. 2011 Nov;132(2):146-57. doi: 10.1016/j.pharmthera.2011.03.008. Epub 2011 Apr 2. Pharmacol Ther. 2011. PMID: 21440001 Free PMC article. Review.

8

Discovery of a novel member of the histamine receptor family.

Nguyen T, Shapiro DA, George SR, Setola V, Lee DK, Cheng R, Rauser L, Lee SP, Lynch KR, Roth BL, O'Dowd BF. Nguyen T, et al. Among authors: setola v. Mol Pharmacol. 2001 Mar;59(3):427-33. doi: 10.1124/mol.59.3.427. Mol Pharmacol. 2001. PMID: 11179435

9

Binding of amine-substituted N1-benzenesulfonylindoles at human 5-HT6 serotonin receptors.

Pullagurla M, Siripurapu U, Kolanos R, Bondarev ML, Dukat M, Setola V, Roth BL, Glennon RA. Pullagurla M, et al. Among authors: setola v. Bioorg Med Chem Lett. 2005 Dec 1;15(23):5298-302. doi: 10.1016/j.bmcl.2005.08.059. Epub 2005 Sep 23. Bioorg Med Chem Lett. 2005. PMID: 16183286

10

1-(1-Naphthyl)piperazine as a novel template for 5-HT6 serotonin receptor ligands.

Lee M, Rangisetty JB, Pullagurla MR, Dukat M, Setola V, Roth BL, Glennon RA. Lee M, et al. Among authors: setola v. Bioorg Med Chem Lett. 2005 Mar 15;15(6):1707-11. doi: 10.1016/j.bmcl.2005.01.031. Bioorg Med Chem Lett. 2005. PMID: 15745826

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