Sawyers CL - Search Results

1

Transcriptional regulation of a metastasis suppressor gene by Tip60 and beta-catenin complexes.

Kim JH, Kim B, Cai L, Choi HJ, Ohgi KA, Tran C, Chen C, Chung CH, Huber O, Rose DW, Sawyers CL, Rosenfeld MG, Baek SH. Kim JH, et al. Among authors: sawyers cl. Nature. 2005 Apr 14;434(7035):921-6. doi: 10.1038/nature03452. Nature. 2005. PMID: 15829968 Free article.

2

NF-kappa B activates prostate-specific antigen expression and is upregulated in androgen-independent prostate cancer.

Chen CD, Sawyers CL. Chen CD, et al. Among authors: sawyers cl. Mol Cell Biol. 2002 Apr;22(8):2862-70. doi: 10.1128/MCB.22.8.2862-2870.2002. Mol Cell Biol. 2002. PMID: 11909978 Free PMC article.

3

Growth inhibitory effects of the dual ErbB1/ErbB2 tyrosine kinase inhibitor PKI-166 on human prostate cancer xenografts.

Mellinghoff IK, Tran C, Sawyers CL. Mellinghoff IK, et al. Among authors: sawyers cl. Cancer Res. 2002 Sep 15;62(18):5254-9. Cancer Res. 2002. PMID: 12234993

4

MicroPET imaging of prostate cancer in LNCAP-SR39TK-GFP mouse xenografts.

Yang H, Berger F, Tran C, Gambhir SS, Sawyers CL. Yang H, et al. Among authors: sawyers cl. Prostate. 2003 Apr 1;55(1):39-47. doi: 10.1002/pros.10208. Prostate. 2003. PMID: 12640659

5

Molecular determinants of resistance to antiandrogen therapy.

Chen CD, Welsbie DS, Tran C, Baek SH, Chen R, Vessella R, Rosenfeld MG, Sawyers CL. Chen CD, et al. Among authors: sawyers cl. Nat Med. 2004 Jan;10(1):33-9. doi: 10.1038/nm972. Epub 2003 Dec 21. Nat Med. 2004. PMID: 14702632

6

HER2/neu kinase-dependent modulation of androgen receptor function through effects on DNA binding and stability.

Mellinghoff IK, Vivanco I, Kwon A, Tran C, Wongvipat J, Sawyers CL. Mellinghoff IK, et al. Among authors: sawyers cl. Cancer Cell. 2004 Nov;6(5):517-27. doi: 10.1016/j.ccr.2004.09.031. Cancer Cell. 2004. PMID: 15542435 Free article.

7

Hypoxia-inducible factor determines sensitivity to inhibitors of mTOR in kidney cancer.

Thomas GV, Tran C, Mellinghoff IK, Welsbie DS, Chan E, Fueger B, Czernin J, Sawyers CL. Thomas GV, et al. Among authors: sawyers cl. Nat Med. 2006 Jan;12(1):122-7. doi: 10.1038/nm1337. Epub 2005 Dec 11. Nat Med. 2006. PMID: 16341243

8

Ligand-specific allosteric regulation of coactivator functions of androgen receptor in prostate cancer cells.

Baek SH, Ohgi KA, Nelson CA, Welsbie D, Chen C, Sawyers CL, Rose DW, Rosenfeld MG. Baek SH, et al. Among authors: sawyers cl. Proc Natl Acad Sci U S A. 2006 Feb 28;103(9):3100-5. doi: 10.1073/pnas.0510842103. Epub 2006 Feb 21. Proc Natl Acad Sci U S A. 2006. PMID: 16492776 Free PMC article.

9

Development of a second-generation antiandrogen for treatment of advanced prostate cancer.

Tran C, Ouk S, Clegg NJ, Chen Y, Watson PA, Arora V, Wongvipat J, Smith-Jones PM, Yoo D, Kwon A, Wasielewska T, Welsbie D, Chen CD, Higano CS, Beer TM, Hung DT, Scher HI, Jung ME, Sawyers CL. Tran C, et al. Among authors: sawyers cl. Science. 2009 May 8;324(5928):787-90. doi: 10.1126/science.1168175. Epub 2009 Apr 9. Science. 2009. PMID: 19359544 Free PMC article. Clinical Trial.

10

Structure-activity relationship for thiohydantoin androgen receptor antagonists for castration-resistant prostate cancer (CRPC).

Jung ME, Ouk S, Yoo D, Sawyers CL, Chen C, Tran C, Wongvipat J. Jung ME, et al. Among authors: sawyers cl. J Med Chem. 2010 Apr 8;53(7):2779-96. doi: 10.1021/jm901488g. J Med Chem. 2010. PMID: 20218717 Free PMC article.

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