Reed MJ - Search Results

1

Novel and potent 17beta-hydroxysteroid dehydrogenase type 1 inhibitors.

Lawrence HR, Vicker N, Allan GM, Smith A, Mahon MF, Tutill HJ, Purohit A, Reed MJ, Potter BV. Lawrence HR, et al. Among authors: reed mj. J Med Chem. 2005 Apr 21;48(8):2759-62. doi: 10.1021/jm049045r. J Med Chem. 2005. PMID: 15828812

2

Estrone 3-sulfate mimics, inhibitors of estrone sulfatase activity: homology model construction and docking studies.

Howarth NM, Purohit A, Robinson JJ, Vicker N, Reed MJ, Potter BV. Howarth NM, et al. Among authors: reed mj. Biochemistry. 2002 Dec 17;41(50):14801-14. doi: 10.1021/bi020543g. Biochemistry. 2002. PMID: 12475228

3

Docking studies of sulphamate inhibitors of estrone sulphatase in human carbonic anhydrase II.

Vicker N, Ho Y, Robinson J, Woo LL, Purohit A, Reed MJ, Potter BV. Vicker N, et al. Among authors: reed mj. Bioorg Med Chem Lett. 2003 Mar 10;13(5):863-5. doi: 10.1016/s0960-894x(03)00009-x. Bioorg Med Chem Lett. 2003. PMID: 12617909

4

D-ring modified estrone derivatives as novel potent inhibitors of steroid sulfatase.

Fischer DS, Woo LW, Mahon MF, Purohit A, Reed MJ, Potter BV. Fischer DS, et al. Among authors: reed mj. Bioorg Med Chem. 2003 Apr 17;11(8):1685-700. doi: 10.1016/s0968-0896(03)00042-7. Bioorg Med Chem. 2003. PMID: 12659755

5

Novel D-ring modified steroid derivatives as potent, non-estrogenic, steroid sulfatase inhibitors with in vivo activity.

Fischer DS, Chander SK, Woo LW, Fenton JC, Purohit A, Reed MJ, Potter BV. Fischer DS, et al. Among authors: reed mj. J Steroid Biochem Mol Biol. 2003 Feb;84(2-3):343-9. doi: 10.1016/s0960-0760(03)00048-7. J Steroid Biochem Mol Biol. 2003. PMID: 12711021

6

First dual aromatase-steroid sulfatase inhibitors.

Woo LW, Sutcliffe OB, Bubert C, Grasso A, Chander SK, Purohit A, Reed MJ, Potter BV. Woo LW, et al. Among authors: reed mj. J Med Chem. 2003 Jul 17;46(15):3193-6. doi: 10.1021/jm034033b. J Med Chem. 2003. PMID: 12852749

7

Synthesis, in vitro and in vivo activity of benzophenone-based inhibitors of steroid sulfatase.

Hejaz HA, Woo LW, Purohit A, Reed MJ, Potter BV. Hejaz HA, et al. Among authors: reed mj. Bioorg Med Chem. 2004 May 15;12(10):2759-72. doi: 10.1016/j.bmc.2004.02.040. Bioorg Med Chem. 2004. PMID: 15110857

8

2-Alkylsulfanyl estrogen derivatives: synthesis of a novel class of multi-targeted anti-tumour agents.

Leese MP, Newman SP, Purohit A, Reed MJ, Potter BV. Leese MP, et al. Among authors: reed mj. Bioorg Med Chem Lett. 2004 Jun 21;14(12):3135-8. doi: 10.1016/j.bmcl.2004.04.027. Bioorg Med Chem Lett. 2004. PMID: 15149660

9

A novel 18 beta-glycyrrhetinic acid analogue as a potent and selective inhibitor of 11 beta-hydroxysteroid dehydrogenase 2.

Vicker N, Su X, Lawrence H, Cruttenden A, Purohit A, Reed MJ, Potter BV. Vicker N, et al. Among authors: reed mj. Bioorg Med Chem Lett. 2004 Jun 21;14(12):3263-7. doi: 10.1016/j.bmcl.2004.03.107. Bioorg Med Chem Lett. 2004. PMID: 15149687

10

Novel 18beta-glycyrrhetinic acid analogues as potent and selective inhibitors of 11beta-hydroxysteroid dehydrogenases.

Su X, Lawrence H, Ganeshapillai D, Cruttenden A, Purohit A, Reed MJ, Vicker N, Potter BV. Su X, et al. Among authors: reed mj. Bioorg Med Chem. 2004 Aug 15;12(16):4439-57. doi: 10.1016/j.bmc.2004.06.008. Bioorg Med Chem. 2004. PMID: 15265495

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