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The Parkinson's disease protein DJ-1 is neuroprotective due to cysteine-sulfinic acid-driven mitochondrial localization.
Canet-Avilés RM, Wilson MA, Miller DW, Ahmad R, McLendon C, Bandyopadhyay S, Baptista MJ, Ringe D, Petsko GA, Cookson MR. Canet-Avilés RM, et al. Among authors: miller dw. Proc Natl Acad Sci U S A. 2004 Jun 15;101(24):9103-8. doi: 10.1073/pnas.0402959101. Epub 2004 Jun 4. Proc Natl Acad Sci U S A. 2004. PMID: 15181200 Free PMC article.
Kinase activity is required for the toxic effects of mutant LRRK2/dardarin.
Greggio E, Jain S, Kingsbury A, Bandopadhyay R, Lewis P, Kaganovich A, van der Brug MP, Beilina A, Blackinton J, Thomas KJ, Ahmad R, Miller DW, Kesavapany S, Singleton A, Lees A, Harvey RJ, Harvey K, Cookson MR. Greggio E, et al. Among authors: miller dw. Neurobiol Dis. 2006 Aug;23(2):329-41. doi: 10.1016/j.nbd.2006.04.001. Epub 2006 Jun 5. Neurobiol Dis. 2006. PMID: 16750377
Caspase-1 causes truncation and aggregation of the Parkinson's disease-associated protein α-synuclein.
Wang W, Nguyen LT, Burlak C, Chegini F, Guo F, Chataway T, Ju S, Fisher OS, Miller DW, Datta D, Wu F, Wu CX, Landeru A, Wells JA, Cookson MR, Boxer MB, Thomas CJ, Gai WP, Ringe D, Petsko GA, Hoang QQ. Wang W, et al. Among authors: miller dw. Proc Natl Acad Sci U S A. 2016 Aug 23;113(34):9587-92. doi: 10.1073/pnas.1610099113. Epub 2016 Aug 1. Proc Natl Acad Sci U S A. 2016. PMID: 27482083 Free PMC article.
718 results