Schärer OD - Search Results

1

Site-specific incorporation of N-(deoxyguanosin-8-yl)-2-acetylaminofluorene (dG-AAF) into oligonucleotides using modified 'ultra-mild' DNA synthesis.

Gillet LC, Alzeer J, Schärer OD. Gillet LC, et al. Among authors: scharer od. Nucleic Acids Res. 2005 Apr 6;33(6):1961-9. doi: 10.1093/nar/gki335. Print 2005. Nucleic Acids Res. 2005. PMID: 15814813 Free PMC article.

2

Development of Comprehensive Ultraperformance Liquid Chromatography-High-Resolution Mass Spectrometry Assays to Quantitate Cisplatin-Induced DNA-DNA Cross-Links.

Groehler AS 4th, Maratova A, Dao NM, Mahkmut A, Schärer OD. Groehler AS 4th, et al. Among authors: scharer od. Chem Res Toxicol. 2023 Jun 19;36(6):822-837. doi: 10.1021/acs.chemrestox.2c00308. Epub 2023 May 19. Chem Res Toxicol. 2023. PMID: 37208809

3

A disease-associated XPA allele interferes with TFIIH binding and primarily affects transcription-coupled nucleotide excision repair.

van den Heuvel D, Kim M, Wondergem AP, van der Meer PJ, Witkamp M, Lambregtse F, Kim HS, Kan F, Apelt K, Kragten A, González-Prieto R, Vertegaal ACO, Yeo JE, Kim BG, van Doorn R, Schärer OD, Luijsterburg MS. van den Heuvel D, et al. Among authors: scharer od. Proc Natl Acad Sci U S A. 2023 Mar 14;120(11):e2208860120. doi: 10.1073/pnas.2208860120. Epub 2023 Mar 9. Proc Natl Acad Sci U S A. 2023. PMID: 36893274 Free PMC article.

4

Preparation of C8-amine and acetylamine adducts of 2'-deoxyguanosine suitably protected for DNA synthesis.

Gillet LC, Schärer OD. Gillet LC, et al. Among authors: scharer od. Org Lett. 2002 Nov 28;4(24):4205-8. doi: 10.1021/ol026474f. Org Lett. 2002. PMID: 12443059

5

Molecular mechanisms of mammalian global genome nucleotide excision repair.

Gillet LC, Schärer OD. Gillet LC, et al. Among authors: scharer od. Chem Rev. 2006 Feb;106(2):253-76. doi: 10.1021/cr040483f. Chem Rev. 2006. PMID: 16464005 Review. No abstract available.

6

A modified thymine for the synthesis of site-specific thymine-guanine DNA interstrand crosslinks.

Alzeer J, Schärer OD. Alzeer J, et al. Among authors: scharer od. Nucleic Acids Res. 2006;34(16):4458-66. doi: 10.1093/nar/gkl587. Epub 2006 Aug 31. Nucleic Acids Res. 2006. PMID: 16945959 Free PMC article.

7

Crosslinking of the NER damage recognition proteins XPC-HR23B, XPA and RPA to photoreactive probes that mimic DNA damages.

Maltseva EA, Rechkunova NI, Gillet LC, Petruseva IO, Schärer OD, Lavrik OI. Maltseva EA, et al. Among authors: scharer od. Biochim Biophys Acta. 2007 May;1770(5):781-9. doi: 10.1016/j.bbagen.2007.01.007. Epub 2007 Jan 25. Biochim Biophys Acta. 2007. PMID: 17320292

8

Domain swapping between FEN-1 and XPG defines regions in XPG that mediate nucleotide excision repair activity and substrate specificity.

Hohl M, Dunand-Sauthier I, Staresincic L, Jaquier-Gubler P, Thorel F, Modesti M, Clarkson SG, Schärer OD. Hohl M, et al. Among authors: scharer od. Nucleic Acids Res. 2007;35(9):3053-63. doi: 10.1093/nar/gkm092. Epub 2007 Apr 22. Nucleic Acids Res. 2007. PMID: 17452369 Free PMC article.

9

Synthesis of DNA interstrand cross-links using a photocaged nucleobase.

Hentschel S, Alzeer J, Angelov T, Schärer OD, Luedtke NW. Hentschel S, et al. Among authors: scharer od. Angew Chem Int Ed Engl. 2012 Apr 2;51(14):3466-9. doi: 10.1002/anie.201108018. Epub 2012 Feb 17. Angew Chem Int Ed Engl. 2012. PMID: 22344895

10

Repair of cisplatin-induced DNA interstrand crosslinks by a replication-independent pathway involving transcription-coupled repair and translesion synthesis.

Enoiu M, Jiricny J, Schärer OD. Enoiu M, et al. Among authors: scharer od. Nucleic Acids Res. 2012 Oct;40(18):8953-64. doi: 10.1093/nar/gks670. Epub 2012 Jul 18. Nucleic Acids Res. 2012. PMID: 22810206 Free PMC article.

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