Heffner TG - Search Results

1

Structure-activity relationships of pregabalin and analogues that target the alpha(2)-delta protein.

Belliotti TR, Capiris T, Ekhato IV, Kinsora JJ, Field MJ, Heffner TG, Meltzer LT, Schwarz JB, Taylor CP, Thorpe AJ, Vartanian MG, Wise LD, Zhi-Su T, Weber ML, Wustrow DJ. Belliotti TR, et al. Among authors: heffner tg. J Med Chem. 2005 Apr 7;48(7):2294-307. doi: 10.1021/jm049762l. J Med Chem. 2005. PMID: 15801823

2

Dopamine autoreceptor agonists as potential antipsychotics. 1. (Aminoalkoxy)anilines.

Jaen JC, Wise LD, Heffner TG, Pugsley TA, Meltzer LT. Jaen JC, et al. Among authors: heffner tg. J Med Chem. 1988 Aug;31(8):1621-5. doi: 10.1021/jm00403a022. J Med Chem. 1988. PMID: 2899647

3

Studies of the active conformation of a novel series of benzamide dopamine D2 agonists.

Wustrow DJ, Wise LD, Cody DM, MacKenzie RG, Georgic LM, Pugsley TA, Heffner TG. Wustrow DJ, et al. Among authors: heffner tg. J Med Chem. 1994 Nov 25;37(24):4251-7. doi: 10.1021/jm00050a022. J Med Chem. 1994. PMID: 7990124

4

Aryl 1-but-3-ynyl-4-phenyl-1,2,3,6-tetrahydropyridines as potential antipsychotic agents: synthesis and structure-activity relationships.

Glase SA, Akunne HC, Heffner TG, Jaen JC, MacKenzie RG, Meltzer LT, Pugsley TA, Smith SJ, Wise LD. Glase SA, et al. Among authors: heffner tg. J Med Chem. 1996 Aug 2;39(16):3179-87. doi: 10.1021/jm950721m. J Med Chem. 1996. PMID: 8759640

5

Chromeno[3,4-c]pyridin-5-ones: selective human dopamine D4 receptor antagonists as potential antipsychotic agents.

Unangst PC, Capiris T, Connor DT, Heffner TG, MacKenzie RG, Miller SR, Pugsley TA, Wise LD. Unangst PC, et al. Among authors: heffner tg. J Med Chem. 1997 Aug 15;40(17):2688-93. doi: 10.1021/jm970170v. J Med Chem. 1997. PMID: 9276014

6

(Aryloxy)alkylamines as selective human dopamine D4 receptor antagonists: potential antipsychotic agents.

Unangst PC, Capiris T, Connor DT, Doubleday R, Heffner TG, MacKenzie RG, Miller SR, Pugsley TA, Wise LD. Unangst PC, et al. Among authors: heffner tg. J Med Chem. 1997 Dec 5;40(25):4026-9. doi: 10.1021/jm970422s. J Med Chem. 1997. PMID: 9406594

7

Pyrazolo[1,5-a]pyrimidine CRF-1 receptor antagonists.

Wustrow DJ, Capiris T, Rubin R, Knobelsdorf JA, Akunne H, Davis MD, MacKenzie R, Pugsley TA, Zoski KT, Heffner TG, Wise LD. Wustrow DJ, et al. Among authors: heffner tg. Bioorg Med Chem Lett. 1998 Aug 18;8(16):2067-70. doi: 10.1016/s0960-894x(98)00372-2. Bioorg Med Chem Lett. 1998. PMID: 9873487

8

Orally active analogues of the dopaminergic prodrug 6-(N,N-di-n-propylamino)-3,4,5,6,7,8-hexahydro-2H-naphthalen-1-one: synthesis and pharmacological activity.

Venhuis BJ, Dijkstra D, Wustrow DJ, Meltzer LT, Wise LD, Johnson SJ, Heffner TG, Wikström HV. Venhuis BJ, et al. Among authors: heffner tg. J Med Chem. 2003 Feb 13;46(4):584-90. doi: 10.1021/jm020990u. J Med Chem. 2003. PMID: 12570379

9

Aminopyrimidines with high affinity for both serotonin and dopamine receptors.

Wustrow D, Belliotti T, Glase S, Kesten SR, Johnson D, Colbry N, Rubin R, Blackburn A, Akunne H, Corbin A, Davis MD, Georgic L, Whetzel S, Zoski K, Heffner T, Pugsley T, Wise L. Wustrow D, et al. J Med Chem. 1998 Feb 26;41(5):760-71. doi: 10.1021/jm9707378. J Med Chem. 1998. PMID: 9513604

10

Dopamine autoreceptor agonists as potential antipsychotics. 2. (Aminoalkoxy)-4H-1-benzopyran-4-ones.

Jaen JC, Wise LD, Heffner TG, Pugsley TA, Meltzer LT. Jaen JC, et al. Among authors: heffner tg. J Med Chem. 1991 Jan;34(1):248-56. doi: 10.1021/jm00105a039. J Med Chem. 1991. PMID: 1671416

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