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A Novel Antigen Design Strategy to Isolate Single-Domain Antibodies that Target Human Nav1.7 and Reduce Pain in Animal Models.
Martina M, Banderali U, Yogi A, Arbabi Ghahroudi M, Liu H, Sulea T, Durocher Y, Hussack G, van Faassen H, Chakravarty B, Liu QY, Iqbal U, Ling B, Lessard E, Sheff J, Robotham A, Callaghan D, Moreno M, Comas T, Ly D, Stanimirovic D. Martina M, et al. Among authors: lessard e. Adv Sci (Weinh). 2024 Oct;11(40):e2405432. doi: 10.1002/advs.202405432. Epub 2024 Aug 29. Adv Sci (Weinh). 2024. PMID: 39206821 Free PMC article.
Preclinical in vivo longitudinal assessment of KG207-M as a disease-modifying Alzheimer's disease therapeutic.
Kang MS, Shin M, Ottoy J, Aliaga AA, Mathotaarachchi S, Quispialaya K, Pascoal TA, Collins DL, Chakravarty MM, Mathieu A, Sandelius Å, Blennow K, Zetterberg H, Massarweh G, Soucy JP, Cuello AC, Gauthier S, Waterston M, Yoganathan N, Lessard E, Haqqani A, Rennie K, Stanimirovic D, Chakravarthy B, Rosa-Neto P. Kang MS, et al. Among authors: lessard e. J Cereb Blood Flow Metab. 2022 May;42(5):788-801. doi: 10.1177/0271678X211035625. Epub 2021 Aug 11. J Cereb Blood Flow Metab. 2022. PMID: 34378436 Free PMC article.
7-Fluorosialyl Glycosides Are Hydrolysis Resistant but Readily Assembled by Sialyltransferases Providing Easy Access to More Metabolically Stable Glycoproteins.
Geissner A, Baumann L, Morley TJ, Wong AKO, Sim L, Rich JR, So PPL, Dullaghan EM, Lessard E, Iqbal U, Moreno M, Wakarchuk WW, Withers SG. Geissner A, et al. Among authors: lessard e. ACS Cent Sci. 2021 Feb 24;7(2):345-354. doi: 10.1021/acscentsci.0c01589. Epub 2021 Jan 19. ACS Cent Sci. 2021. PMID: 33655072 Free PMC article.
69 results