Guertin DA - Search Results

1

Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex.

Sarbassov DD, Guertin DA, Ali SM, Sabatini DM. Sarbassov DD, et al. Among authors: guertin da. Science. 2005 Feb 18;307(5712):1098-101. doi: 10.1126/science.1106148. Science. 2005. PMID: 15718470

2

Rictor, a novel binding partner of mTOR, defines a rapamycin-insensitive and raptor-independent pathway that regulates the cytoskeleton.

Sarbassov DD, Ali SM, Kim DH, Guertin DA, Latek RR, Erdjument-Bromage H, Tempst P, Sabatini DM. Sarbassov DD, et al. Among authors: guertin da. Curr Biol. 2004 Jul 27;14(14):1296-302. doi: 10.1016/j.cub.2004.06.054. Curr Biol. 2004. PMID: 15268862 Free article.

3

RNAi living-cell microarrays for loss-of-function screens in Drosophila melanogaster cells.

Wheeler DB, Bailey SN, Guertin DA, Carpenter AE, Higgins CO, Sabatini DM. Wheeler DB, et al. Among authors: guertin da. Nat Methods. 2004 Nov;1(2):127-32. doi: 10.1038/nmeth711. Epub 2004 Oct 21. Nat Methods. 2004. PMID: 15782175

4

An expanding role for mTOR in cancer.

Guertin DA, Sabatini DM. Guertin DA, et al. Trends Mol Med. 2005 Aug;11(8):353-61. doi: 10.1016/j.molmed.2005.06.007. Trends Mol Med. 2005. PMID: 16002336 Review.

5

Functional genomics identifies TOR-regulated genes that control growth and division.

Guertin DA, Guntur KV, Bell GW, Thoreen CC, Sabatini DM. Guertin DA, et al. Curr Biol. 2006 May 23;16(10):958-70. doi: 10.1016/j.cub.2006.03.084. Curr Biol. 2006. PMID: 16713952 Free article.

6

CellProfiler: image analysis software for identifying and quantifying cell phenotypes.

Carpenter AE, Jones TR, Lamprecht MR, Clarke C, Kang IH, Friman O, Guertin DA, Chang JH, Lindquist RA, Moffat J, Golland P, Sabatini DM. Carpenter AE, et al. Among authors: guertin da. Genome Biol. 2006;7(10):R100. doi: 10.1186/gb-2006-7-10-r100. Epub 2006 Oct 31. Genome Biol. 2006. PMID: 17076895 Free PMC article.

7

Ablation in mice of the mTORC components raptor, rictor, or mLST8 reveals that mTORC2 is required for signaling to Akt-FOXO and PKCalpha, but not S6K1.

Guertin DA, Stevens DM, Thoreen CC, Burds AA, Kalaany NY, Moffat J, Brown M, Fitzgerald KJ, Sabatini DM. Guertin DA, et al. Dev Cell. 2006 Dec;11(6):859-71. doi: 10.1016/j.devcel.2006.10.007. Dev Cell. 2006. PMID: 17141160 Free article.

8

Defining the role of mTOR in cancer.

Guertin DA, Sabatini DM. Guertin DA, et al. Cancer Cell. 2007 Jul;12(1):9-22. doi: 10.1016/j.ccr.2007.05.008. Cancer Cell. 2007. PMID: 17613433 Free article. Review.

9

mTOR complex 2 is required for the development of prostate cancer induced by Pten loss in mice.

Guertin DA, Stevens DM, Saitoh M, Kinkel S, Crosby K, Sheen JH, Mullholland DJ, Magnuson MA, Wu H, Sabatini DM. Guertin DA, et al. Cancer Cell. 2009 Feb 3;15(2):148-59. doi: 10.1016/j.ccr.2008.12.017. Cancer Cell. 2009. PMID: 19185849 Free PMC article.

10

The pharmacology of mTOR inhibition.

Guertin DA, Sabatini DM. Guertin DA, et al. Sci Signal. 2009 Apr 21;2(67):pe24. doi: 10.1126/scisignal.267pe24. Sci Signal. 2009. PMID: 19383975

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