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An inducible caspase 9 safety switch for T-cell therapy.
Straathof KC, Pulè MA, Yotnda P, Dotti G, Vanin EF, Brenner MK, Heslop HE, Spencer DM, Rooney CM. Straathof KC, et al. Blood. 2005 Jun 1;105(11):4247-54. doi: 10.1182/blood-2004-11-4564. Epub 2005 Feb 22. Blood. 2005. PMID: 15728125 Free PMC article.
Complete responses of relapsed lymphoma following genetic modification of tumor-antigen presenting cells and T-lymphocyte transfer.
Bollard CM, Gottschalk S, Leen AM, Weiss H, Straathof KC, Carrum G, Khalil M, Wu MF, Huls MH, Chang CC, Gresik MV, Gee AP, Brenner MK, Rooney CM, Heslop HE. Bollard CM, et al. Among authors: straathof kc. Blood. 2007 Oct 15;110(8):2838-45. doi: 10.1182/blood-2007-05-091280. Epub 2007 Jul 3. Blood. 2007. PMID: 17609424 Free PMC article. Clinical Trial.
Inducible apoptosis as a safety switch for adoptive cell therapy.
Di Stasi A, Tey SK, Dotti G, Fujita Y, Kennedy-Nasser A, Martinez C, Straathof K, Liu E, Durett AG, Grilley B, Liu H, Cruz CR, Savoldo B, Gee AP, Schindler J, Krance RA, Heslop HE, Spencer DM, Rooney CM, Brenner MK. Di Stasi A, et al. N Engl J Med. 2011 Nov 3;365(18):1673-83. doi: 10.1056/NEJMoa1106152. N Engl J Med. 2011. PMID: 22047558 Free PMC article. Clinical Trial.
Cytotoxic T lymphocyte therapy for Epstein-Barr virus+ Hodgkin's disease.
Bollard CM, Aguilar L, Straathof KC, Gahn B, Huls MH, Rousseau A, Sixbey J, Gresik MV, Carrum G, Hudson M, Dilloo D, Gee A, Brenner MK, Rooney CM, Heslop HE. Bollard CM, et al. Among authors: straathof kc. J Exp Med. 2004 Dec 20;200(12):1623-33. doi: 10.1084/jem.20040890. J Exp Med. 2004. PMID: 15611290 Free PMC article.
Suicide genes as safety switches in T lymphocytes.
Straathof KC, Spencer DM, Sutton RE, Rooney CM. Straathof KC, et al. Cytotherapy. 2003;5(3):227-30. doi: 10.1080/14653240310001497. Cytotherapy. 2003. PMID: 12850790 Review.
37 results