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Page 1
An intracellular conformational sensor assay for Abl T315I.
Zhou V, Gao X, Han S, Brinker A, Caldwell JS, Gu XJ. Zhou V, et al. Among authors: brinker a. Anal Biochem. 2009 Feb 15;385(2):300-8. doi: 10.1016/j.ab.2008.11.015. Epub 2008 Nov 20. Anal Biochem. 2009. PMID: 19059193
In silico activity profiling reveals the mechanism of action of antimalarials discovered in a high-throughput screen.
Plouffe D, Brinker A, McNamara C, Henson K, Kato N, Kuhen K, Nagle A, Adrián F, Matzen JT, Anderson P, Nam TG, Gray NS, Chatterjee A, Janes J, Yan SF, Trager R, Caldwell JS, Schultz PG, Zhou Y, Winzeler EA. Plouffe D, et al. Among authors: brinker a. Proc Natl Acad Sci U S A. 2008 Jul 1;105(26):9059-64. doi: 10.1073/pnas.0802982105. Epub 2008 Jun 25. Proc Natl Acad Sci U S A. 2008. PMID: 18579783 Free PMC article.
Time-resolved fluorescence resonance energy transfer and surface plasmon resonance-based assays for retinoid and transthyretin binding to retinol-binding protein 4.
Sharif O, Hu H, Klock H, Hampton EN, Nigoghossian E, Knuth MW, Matzen J, Anderson P, Trager R, Uno T, Glynne RJ, Azarian SM, Caldwell JS, Brinker A. Sharif O, et al. Among authors: brinker a. Anal Biochem. 2009 Sep 15;392(2):162-8. doi: 10.1016/j.ab.2009.05.038. Epub 2009 May 29. Anal Biochem. 2009. PMID: 19482004
In vivo incorporation of unnatural amino acids to probe structure, dynamics, and ligand binding in a large protein by nuclear magnetic resonance spectroscopy.
Cellitti SE, Jones DH, Lagpacan L, Hao X, Zhang Q, Hu H, Brittain SM, Brinker A, Caldwell J, Bursulaya B, Spraggon G, Brock A, Ryu Y, Uno T, Schultz PG, Geierstanger BH. Cellitti SE, et al. Among authors: brinker a. J Am Chem Soc. 2008 Jul 23;130(29):9268-81. doi: 10.1021/ja801602q. Epub 2008 Jun 25. J Am Chem Soc. 2008. PMID: 18576636 Free PMC article.
185 results