Qin W - Search Results

1

Changes of primary sequence and secondary structure proximal to the 5' end of the stop codon substantially increases the expression of the variable region of an antibody in E. coli.

Qin W, Feng J, Li Y, Lin Z, Shen B. Qin W, et al. Biotechnol Lett. 2005 Jan;27(2):131-4. doi: 10.1007/s10529-004-7660-4. Biotechnol Lett. 2005. PMID: 15703877

2

A novel TNFalpha antagonizing peptide-Fc fusion protein designed based on CDRs of TNFalpha neutralizing monoclonal antibody.

Qin W, Feng J, Zhang W, Li Y, Shen B. Qin W, et al. Biochem Biophys Res Commun. 2004 Sep 24;322(3):1024-8. doi: 10.1016/j.bbrc.2004.07.208. Biochem Biophys Res Commun. 2004. PMID: 15336567

3

Fusion protein of CDR mimetic peptide with Fc inhibit TNF-alpha induced cytotoxicity.

Qin W, Feng J, Li Y, Lin Z, Shen B. Qin W, et al. Mol Immunol. 2006 Feb;43(6):660-6. doi: 10.1016/j.molimm.2005.04.009. Mol Immunol. 2006. PMID: 15878201

4

De novo design TNF-alpha antagonistic peptide based on the complex structure of TNF-alpha with its neutralizing monoclonal antibody Z12.

Qin W, Feng J, Li Y, Lin Z, Shen B. Qin W, et al. J Biotechnol. 2006 Aug 20;125(1):57-63. doi: 10.1016/j.jbiotec.2006.01.036. Epub 2006 Mar 7. J Biotechnol. 2006. PMID: 16522339

5

A novel human scFv fragment against TNF-alpha from de novo design method.

Chang H, Qin W, Li Y, Zhang J, Lin Z, Lv M, Sun Y, Feng J, Shen B. Chang H, et al. Among authors: qin w. Mol Immunol. 2007 Jul;44(15):3789-96. doi: 10.1016/j.molimm.2007.03.020. Epub 2007 May 7. Mol Immunol. 2007. PMID: 17485112

6

[Establishment of a cell model targeted to NFAT signal transduction pathway for preliminary screening of FK506-like immunosuppressants].

Xiao H, Qian L, Qin WS, Li S, Shen BF, Li Y. Xiao H, et al. Sheng Wu Gong Cheng Xue Bao. 2005 Sep;21(5):759-65. Sheng Wu Gong Cheng Xue Bao. 2005. PMID: 16285518 Chinese.

7

[The expression, renaturation, purification and preliminary identification of human IgE Cepsilon3-Cepsilon4].

Qiao CX, Lin Z, Hu MR, Liu R, Qin WS, Feng JN, Shen BF. Qiao CX, et al. Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi. 2006 Jan;22(1):64-6, 70. Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi. 2006. PMID: 16388748 Chinese.

8

Structure-based design and characterization of a Novel IL-6 antagonist peptide.

Yang Z, Feng J, Li Y, Hu M, Song L, Yu M, Qin W, Shen B. Yang Z, et al. Among authors: qin w. Mol Immunol. 2005 May;42(9):1015-21. doi: 10.1016/j.molimm.2004.09.033. Epub 2004 Nov 23. Mol Immunol. 2005. PMID: 15829291

9

The rational designed antagonist derived from the complex structure of interleukin-6 and its receptor affectively blocking interleukin-6 might be a promising treatment in multiple myeloma.

Feng J, Yang Z, Li Y, Hu M, Yu M, Qin W, Sun J, Shen B. Feng J, et al. Among authors: qin w. Biochimie. 2006 Sep;88(9):1265-73. doi: 10.1016/j.biochi.2006.03.003. Epub 2006 Mar 31. Biochimie. 2006. PMID: 16626851

10

A novel domain antibody rationally designed against TNF-alpha using variable region of human heavy chain antibody as scaffolds to display antagonistic peptides.

Qin W, Feng J, Li Y, Lin Z, Shen B. Qin W, et al. Mol Immunol. 2007 Mar;44(9):2355-61. doi: 10.1016/j.molimm.2006.10.016. Epub 2006 Nov 27. Mol Immunol. 2007. PMID: 17125837

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