do Rosário V - Search Results

1

Imidazolidin-4-one derivatives of primaquine as novel transmission-blocking antimalarials.

Araújo MJ, Bom J, Capela R, Casimiro C, Chambel P, Gomes P, Iley J, Lopes F, Morais J, Moreira R, de Oliveira E, do Rosário V, Vale N. Araújo MJ, et al. Among authors: do rosario v. J Med Chem. 2005 Feb 10;48(3):888-92. doi: 10.1021/jm0494624. J Med Chem. 2005. PMID: 15689174

2

Primaquine dipeptide derivatives bearing an imidazolidin-4-one moiety at the N-terminus as potential antimalarial prodrugs.

Vale N, Nogueira F, do Rosário VE, Gomes P, Moreira R. Vale N, et al. Eur J Med Chem. 2009 Jun;44(6):2506-16. doi: 10.1016/j.ejmech.2009.01.018. Epub 2009 Jan 29. Eur J Med Chem. 2009. PMID: 19232784

3

Imidazoquines as antimalarial and antipneumocystis agents.

Vale N, Prudêncio M, Marques CA, Collins MS, Gut J, Nogueira F, Matos J, Rosenthal PJ, Cushion MT, do Rosário VE, Mota MM, Moreira R, Gomes P. Vale N, et al. J Med Chem. 2009 Dec 10;52(23):7800-7. doi: 10.1021/jm900738c. J Med Chem. 2009. PMID: 19799426 Free PMC article.

4

A carbamate-based approach to primaquine prodrugs: antimalarial activity, chemical stability and enzymatic activation.

Mata G, do Rosário VE, Iley J, Constantino L, Moreira R. Mata G, et al. Bioorg Med Chem. 2012 Jan 15;20(2):886-92. doi: 10.1016/j.bmc.2011.11.059. Epub 2011 Dec 3. Bioorg Med Chem. 2012. PMID: 22189276

5

Imidazolidin-4-one peptidomimetic derivatives of primaquine: synthesis and antimalarial activity.

Vale N, Matos J, Gut J, Nogueira F, do Rosário V, Rosenthal PJ, Moreira R, Gomes P. Vale N, et al. Among authors: do rosario v. Bioorg Med Chem Lett. 2008 Jul 15;18(14):4150-3. doi: 10.1016/j.bmcl.2008.05.076. Epub 2008 May 23. Bioorg Med Chem Lett. 2008. PMID: 18539459

6

Novel potent metallocenes against liver stage malaria.

Matos J, da Cruz FP, Cabrita É, Gut J, Nogueira F, do Rosário VE, Moreira R, Rosenthal PJ, Prudêncio M, Gomes P. Matos J, et al. Antimicrob Agents Chemother. 2012 Mar;56(3):1564-70. doi: 10.1128/AAC.05345-11. Epub 2011 Dec 12. Antimicrob Agents Chemother. 2012. PMID: 22155838 Free PMC article.

7

Dipeptide derivatives of primaquine as transmission-blocking antimalarials: effect of aliphatic side-chain acylation on the gametocytocidal activity and on the formation of carboxyprimaquine in rat liver homogenates.

Portela MJ, Moreira R, Valente E, Constantino L, Iley J, Pinto J, Rosa R, Cravo P, do Rosário VE. Portela MJ, et al. Among authors: do rosario ve. Pharm Res. 1999 Jun;16(6):949-55. doi: 10.1023/a:1018922425551. Pharm Res. 1999. PMID: 10397619

8

Metabolism of primaquine by liver homogenate fractions. Evidence for monoamine oxidase and cytochrome P450 involvement in the oxidative deamination of primaquine to carboxyprimaquine.

Constantino L, Paixão P, Moreira R, Portela MJ, Do Rosario VE, Iley J. Constantino L, et al. Among authors: do rosario ve. Exp Toxicol Pathol. 1999 Jul;51(4-5):299-303. doi: 10.1016/S0940-2993(99)80010-4. Exp Toxicol Pathol. 1999. PMID: 10445386

9

Effect of synthesized inhibitors on babesipain-1, a new cysteine protease from the bovine piroplasm Babesia bigemina.

Martins TM, Gonçalves LM, Capela R, Moreira R, do Rosário VE, Domingos A. Martins TM, et al. Among authors: do rosario ve. Transbound Emerg Dis. 2010 Apr;57(1-2):68-9. doi: 10.1111/j.1865-1682.2010.01102.x. Transbound Emerg Dis. 2010. PMID: 20537109

10

Detection of atovaquone-proguanil resistance conferring mutations in Plasmodium falciparum cytochrome b gene in Luanda, Angola.

Pimentel S, Nogueira F, Benchimol C, Quinhentos V, Bom J, Varandas L, do Rosário V, Bernardino L. Pimentel S, et al. Among authors: do rosario v. Malar J. 2006 Apr 5;5:30. doi: 10.1186/1475-2875-5-30. Malar J. 2006. PMID: 16597338 Free PMC article.

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