Schmechel DE - Search Results

1

Human apoE4-targeted replacement mice display synaptic deficits in the absence of neuropathology.

Wang C, Wilson WA, Moore SD, Mace BE, Maeda N, Schmechel DE, Sullivan PM. Wang C, et al. Among authors: schmechel de. Neurobiol Dis. 2005 Mar;18(2):390-8. doi: 10.1016/j.nbd.2004.10.013. Neurobiol Dis. 2005. PMID: 15686968

2

Human apolipoprotein E4 targeted replacement mice show increased prevalence of intracerebral hemorrhage associated with vascular amyloid deposition.

Sullivan PM, Mace BE, Estrada JC, Schmechel DE, Alberts MJ. Sullivan PM, et al. Among authors: schmechel de. J Stroke Cerebrovasc Dis. 2008 Sep;17(5):303-11. doi: 10.1016/j.jstrokecerebrovasdis.2008.03.011. J Stroke Cerebrovasc Dis. 2008. PMID: 18755411

3

Human apolipoprotein E2, E3, and E4 isoform-specific transgenic mice: human-like pattern of glial and neuronal immunoreactivity in central nervous system not observed in wild-type mice.

Xu PT, Schmechel D, Rothrock-Christian T, Burkhart DS, Qiu HL, Popko B, Sullivan P, Maeda N, Saunders AM, Roses AD, Gilbert JR. Xu PT, et al. Neurobiol Dis. 1996;3(3):229-45. doi: 10.1006/nbdi.1996.0023. Neurobiol Dis. 1996. PMID: 8980023

4

Marked regional differences of brain human apolipoprotein E expression in targeted replacement mice.

Sullivan PM, Mace BE, Maeda N, Schmechel DE. Sullivan PM, et al. Among authors: schmechel de. Neuroscience. 2004;124(4):725-33. doi: 10.1016/j.neuroscience.2003.10.011. Neuroscience. 2004. PMID: 15026113

5

Initial observations of key features of age-related macular degeneration in APOE targeted replacement mice.

Malek G, Mace B, Saloupis P, Schmechel D, Rickman D, Sullivan P, Rickman CB. Malek G, et al. Adv Exp Med Biol. 2006;572:109-17. doi: 10.1007/0-387-32442-9_17. Adv Exp Med Biol. 2006. PMID: 17249563 No abstract available.

6

Cis-acting human ApoE tissue expression element is associated with human pattern of intraneuronal ApoE in transgenic mice.

Roses AD, Gilbert J, Xu PT, Sullivan P, Popko B, Burkhart DS, Christian-Rothrock T, Saunders AM, Maeda N, Schmechel DE. Roses AD, et al. Among authors: schmechel de. Neurobiol Aging. 1998 Jan-Feb;19(1 Suppl):S53-8. doi: 10.1016/s0197-4580(98)00030-x. Neurobiol Aging. 1998. PMID: 9562469

7

Apolipoprotein E allele-dependent pathogenesis: a model for age-related retinal degeneration.

Malek G, Johnson LV, Mace BE, Saloupis P, Schmechel DE, Rickman DW, Toth CA, Sullivan PM, Bowes Rickman C. Malek G, et al. Among authors: schmechel de. Proc Natl Acad Sci U S A. 2005 Aug 16;102(33):11900-5. doi: 10.1073/pnas.0503015102. Epub 2005 Aug 3. Proc Natl Acad Sci U S A. 2005. PMID: 16079201 Free PMC article.

8

Differences in apolipoprotein E3/3 and E4/4 allele-specific gene expression in hippocampus in Alzheimer disease.

Xu PT, Li YJ, Qin XJ, Scherzer CR, Xu H, Schmechel DE, Hulette CM, Ervin J, Gullans SR, Haines J, Pericak-Vance MA, Gilbert JR. Xu PT, et al. Among authors: schmechel de. Neurobiol Dis. 2006 Feb;21(2):256-75. doi: 10.1016/j.nbd.2005.07.004. Epub 2005 Sep 29. Neurobiol Dis. 2006. PMID: 16198584

9

APOE and the regulation of microglial nitric oxide production: a link between genetic risk and oxidative stress.

Colton CA, Brown CM, Cook D, Needham LK, Xu Q, Czapiga M, Saunders AM, Schmechel DE, Rasheed K, Vitek MP. Colton CA, et al. Among authors: schmechel de. Neurobiol Aging. 2002 Sep-Oct;23(5):777-85. doi: 10.1016/s0197-4580(02)00016-7. Neurobiol Aging. 2002. PMID: 12392781

10

Sialylated human apolipoprotein E (apoEs) is preferentially associated with neuron-enriched cultures from APOE transgenic mice.

Xu PT, Schmechel D, Qiu HL, Herbstreith M, Rothrock-Christian T, Eyster M, Roses AD, Gilbert JR. Xu PT, et al. Neurobiol Dis. 1999 Feb;6(1):63-75. doi: 10.1006/nbdi.1998.0213. Neurobiol Dis. 1999. PMID: 10078974

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