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Page 1
Potent and selective MC-4 receptor agonists based on a novel disulfide scaffold.
Yan LZ, Flora D, Edwards P, Smiley DL, Emmerson PJ, Hsiung HM, Gadski R, Hertel J, Heiman ML, Husain S, O'Brien TP, Kahl SD, Zhang L, Dimarchi RD, Mayer JP. Yan LZ, et al. Among authors: flora d. Bioorg Med Chem Lett. 2005 Oct 15;15(20):4611-4. doi: 10.1016/j.bmcl.2005.06.081. Bioorg Med Chem Lett. 2005. PMID: 16105738
Discovery of potent, cyclic calcitonin gene-related peptide receptor antagonists.
Yan LZ, Johnson KW, Rothstein E, Flora D, Edwards P, Li B, Li J, Lynch R, Vaughn R, Clemens-Smith A, McCarty D, Chow C, McKnight KL, Lu J, Nisenbaum ES, Mayer JP. Yan LZ, et al. Among authors: flora d. J Pept Sci. 2011 May;17(5):383-6. doi: 10.1002/psc.1358. Epub 2011 Mar 15. J Pept Sci. 2011. PMID: 21412957
Discovery of a beta-MSH-derived MC-4R selective agonist.
Mayer JP, Hsiung HM, Flora DB, Edwards P, Smith DP, Zhang XY, Gadski RA, Heiman ML, Hertel JL, Emmerson PJ, Husain S, O'brien TP, Kahl SD, Smiley DL, Zhang L, Dimarchi RD, Yan LZ. Mayer JP, et al. Among authors: flora db. J Med Chem. 2005 May 5;48(9):3095-8. doi: 10.1021/jm0501432. J Med Chem. 2005. PMID: 15857110
Concise synthetic routes to human insulin.
Liu F, Luo EY, Flora DB, Mayer JP. Liu F, et al. Org Lett. 2013 Feb 15;15(4):960-3. doi: 10.1021/ol400149j. Epub 2013 Feb 7. Org Lett. 2013. PMID: 23391097
148 results