Knuutila S - Search Results

1

Comprehensive characterization of HNPCC-related colorectal cancers reveals striking molecular features in families with no germline mismatch repair gene mutations.

Abdel-Rahman WM, Ollikainen M, Kariola R, Järvinen HJ, Mecklin JP, Nyström-Lahti M, Knuutila S, Peltomäki P. Abdel-Rahman WM, et al. Among authors: knuutila s. Oncogene. 2005 Feb 24;24(9):1542-51. doi: 10.1038/sj.onc.1208387. Oncogene. 2005. PMID: 15674332

2

Genome-wide allelotyping of 104 Finnish colorectal cancers reveals an excess of allelic imbalance in chromosome 20q in familial cases.

Laiho P, Hienonen T, Karhu A, Lipton L, Aalto Y, Thomas HJ, Birkenkamp-Demtroder K, Hodgson S, Salovaara R, Mecklin JP, Järvinen H, Knuutila S, Halford S, Ørntoft TF, Tomlinson I, Launonen V, Houlston R, Aaltonen LA. Laiho P, et al. Among authors: knuutila s. Oncogene. 2003 Apr 10;22(14):2206-14. doi: 10.1038/sj.onc.1206294. Oncogene. 2003. PMID: 12687022

3

Restoring mismatch repair does not stop the formation of reciprocal translocations in the colon cancer cell line HCA7 but further destabilizes chromosome number.

Abdel-Rahman WM, Lohi H, Knuutila S, Peltomäki P. Abdel-Rahman WM, et al. Among authors: knuutila s. Oncogene. 2005 Jan 20;24(4):706-13. doi: 10.1038/sj.onc.1208129. Oncogene. 2005. PMID: 15580308

4

The Role of Chromosomal Instability and Epigenetics in Colorectal Cancers Lacking β-Catenin/TCF Regulated Transcription.

Abdel-Rahman WM, Lotsari-Salomaa JE, Kaur S, Niskakoski A, Knuutila S, Järvinen H, Mecklin JP, Peltomäki P. Abdel-Rahman WM, et al. Among authors: knuutila s. Gastroenterol Res Pract. 2016;2016:6089658. doi: 10.1155/2016/6089658. Epub 2016 Mar 7. Gastroenterol Res Pract. 2016. PMID: 27047543 Free PMC article.

5

DNA methylation changes and somatic mutations as tumorigenic events in Lynch syndrome-associated adenomas retaining mismatch repair protein expression.

Mäki-Nevala S, Valo S, Ristimäki A, Sarhadi V, Knuutila S, Nyström M, Renkonen-Sinisalo L, Lepistö A, Mecklin JP, Peltomäki P. Mäki-Nevala S, et al. Among authors: knuutila s. EBioMedicine. 2019 Jan;39:280-291. doi: 10.1016/j.ebiom.2018.12.018. Epub 2018 Dec 18. EBioMedicine. 2019. PMID: 30578081 Free PMC article.

6

Truncation of MBD4 predisposes to reciprocal chromosomal translocations and alters the response to therapeutic agents in colon cancer cells.

Abdel-Rahman WM, Knuutila S, Peltomäki P, Harrison DJ, Bader SA. Abdel-Rahman WM, et al. Among authors: knuutila s. DNA Repair (Amst). 2008 Feb 1;7(2):321-8. doi: 10.1016/j.dnarep.2007.11.009. Epub 2007 Dec 26. DNA Repair (Amst). 2008. PMID: 18162445

7

Epigenetic signatures of familial cancer are characteristic of tumor type and family category.

Joensuu EI, Abdel-Rahman WM, Ollikainen M, Ruosaari S, Knuutila S, Peltomäki P. Joensuu EI, et al. Among authors: knuutila s. Cancer Res. 2008 Jun 15;68(12):4597-605. doi: 10.1158/0008-5472.CAN-07-6645. Cancer Res. 2008. PMID: 18559504

8

Potential role of a navigator gene NAV3 in colorectal cancer.

Carlsson E, Ranki A, Sipilä L, Karenko L, Abdel-Rahman WM, Ovaska K, Siggberg L, Aapola U, Ässämäki R, Häyry V, Niiranen K, Helle M, Knuutila S, Hautaniemi S, Peltomäki P, Krohn K. Carlsson E, et al. Among authors: knuutila s. Br J Cancer. 2012 Jan 31;106(3):517-24. doi: 10.1038/bjc.2011.553. Epub 2011 Dec 15. Br J Cancer. 2012. PMID: 22173670 Free PMC article.

9

Differential roles of EPS8 in carcinogenesis: loss of protein expression in a subset of colorectal carcinoma and adenoma.

Abdel-Rahman WM, Ruosaari S, Knuutila S, Peltomäki P. Abdel-Rahman WM, et al. Among authors: knuutila s. World J Gastroenterol. 2012 Aug 7;18(29):3896-903. doi: 10.3748/wjg.v18.i29.3896. World J Gastroenterol. 2012. PMID: 22876043 Free PMC article.

10

Few FH mutations in sporadic counterparts of tumor types observed in hereditary leiomyomatosis and renal cell cancer families.

Kiuru M, Lehtonen R, Arola J, Salovaara R, Järvinen H, Aittomäki K, Sjöberg J, Visakorpi T, Knuutila S, Isola J, Delahunt B, Herva R, Launonen V, Karhu A, Aaltonen LA. Kiuru M, et al. Among authors: knuutila s. Cancer Res. 2002 Aug 15;62(16):4554-7. Cancer Res. 2002. PMID: 12183404

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