Lu X - Search Results

1

1-(Phenyl)isoquinoline carboxamides: a novel class of subtype selective inhibitors of thyrotropin-releasing hormone (TRH) receptors.

Jiang JK, Thomas CJ, Neumann S, Lu X, Rice KC, Gershengorn MC. Jiang JK, et al. Among authors: lu x. Bioorg Med Chem Lett. 2005 Feb 1;15(3):733-6. doi: 10.1016/j.bmcl.2004.11.017. Bioorg Med Chem Lett. 2005. PMID: 15664847

2

Pharmacological studies of thyrotropin-releasing hormone (TRH) receptors from Xenopus laevis: is xTRHR3 a TRH receptor?

Lu X, Bidaud I, Ladram A, Gershengorn MC. Lu X, et al. Endocrinology. 2003 May;144(5):1842-6. doi: 10.1210/en.2002-221074. Endocrinology. 2003. PMID: 12697690

3

A model of inverse agonist action at thyrotropin-releasing hormone receptor type 1: role of a conserved tryptophan in helix 6.

Lu X, Huang W, Worthington S, Drabik P, Osman R, Gershengorn MC. Lu X, et al. Mol Pharmacol. 2004 Nov;66(5):1192-200. doi: 10.1124/mol.104.000349. Epub 2004 Aug 11. Mol Pharmacol. 2004. PMID: 15306657

4

Thyrotropin-releasing hormone (TRH) analogues that exhibit selectivity to TRH receptor subtype 2.

Kaur N, Lu X, Gershengorn MC, Jain R. Kaur N, et al. Among authors: lu x. J Med Chem. 2005 Sep 22;48(19):6162-5. doi: 10.1021/jm0505462. J Med Chem. 2005. PMID: 16162016

5

Synthesis, receptor binding, and activation studies of N(1)-alkyl-L-histidine containing thyrotropin-releasing hormone (TRH) analogues.

Kaur N, Monga V, Josan JS, Lu X, Gershengorn MC, Jain R. Kaur N, et al. Among authors: lu x. Bioorg Med Chem. 2006 Sep 1;14(17):5981-8. doi: 10.1016/j.bmc.2006.05.031. Epub 2006 Jun 2. Bioorg Med Chem. 2006. PMID: 16735122

6

Modifications of the pyroglutamic acid and histidine residues in thyrotropin-releasing hormone (TRH) yield analogs with selectivity for TRH receptor type 2 over type 1.

Kaur N, Monga V, Lu X, Gershengorn MC, Jain R. Kaur N, et al. Among authors: lu x. Bioorg Med Chem. 2007 Jan 1;15(1):433-43. doi: 10.1016/j.bmc.2006.09.045. Epub 2006 Oct 10. Bioorg Med Chem. 2007. PMID: 17035026

7

Thyrotropin-releasing hormone receptors -- similarities and differences.

Sun Y, Lu X, Gershengorn MC. Sun Y, et al. Among authors: lu x. J Mol Endocrinol. 2003 Apr;30(2):87-97. doi: 10.1677/jme.0.0300087. J Mol Endocrinol. 2003. PMID: 12683933 Review.

8

Synthesis, receptor binding, and CNS pharmacological studies of new thyrotropin-releasing hormone (TRH) analogues.

Monga V, Meena CL, Rajput S, Pawar C, Sharma SS, Lu X, Gershengorn MC, Jain R. Monga V, et al. Among authors: lu x. ChemMedChem. 2011 Mar 7;6(3):531-43. doi: 10.1002/cmdc.201000481. Epub 2011 Feb 7. ChemMedChem. 2011. PMID: 21302359 Free PMC article.

9

Regulator of G protein signaling 4 suppresses basal and thyrotropin releasing-hormone (TRH)-stimulated signaling by two mouse TRH receptors, TRH-R(1) and TRH-R(2).

Harder S, Lu X, Wang W, Buck F, Gershengorn MC, Bruhn TO. Harder S, et al. Among authors: lu x. Endocrinology. 2001 Mar;142(3):1188-94. doi: 10.1210/endo.142.3.8019. Endocrinology. 2001. PMID: 11181534

10

The extracellular calcium-sensing receptor is required for cholecystokinin secretion in response to L-phenylalanine in acutely isolated intestinal I cells.

Liou AP, Sei Y, Zhao X, Feng J, Lu X, Thomas C, Pechhold S, Raybould HE, Wank SA. Liou AP, et al. Among authors: lu x. Am J Physiol Gastrointest Liver Physiol. 2011 Apr;300(4):G538-46. doi: 10.1152/ajpgi.00342.2010. Epub 2011 Jan 20. Am J Physiol Gastrointest Liver Physiol. 2011. PMID: 21252045 Free PMC article.

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