Gershengorn MC - Search Results

1

1-(Phenyl)isoquinoline carboxamides: a novel class of subtype selective inhibitors of thyrotropin-releasing hormone (TRH) receptors.

Jiang JK, Thomas CJ, Neumann S, Lu X, Rice KC, Gershengorn MC. Jiang JK, et al. Among authors: gershengorn mc. Bioorg Med Chem Lett. 2005 Feb 1;15(3):733-6. doi: 10.1016/j.bmcl.2004.11.017. Bioorg Med Chem Lett. 2005. PMID: 15664847

2

Thyrotropin releasing hormone analogs: a building block approach to the construction of tetracyclic peptidomimetics.

Chu W, Perlman JH, Gershengorn MC, Moeller KD. Chu W, et al. Among authors: gershengorn mc. Bioorg Med Chem Lett. 1998 Nov 3;8(21):3093-6. doi: 10.1016/S0960-894X(98)00567-8. Bioorg Med Chem Lett. 1998. PMID: 9873682 Free article.

3

Regulator of G protein signaling 4 suppresses basal and thyrotropin releasing-hormone (TRH)-stimulated signaling by two mouse TRH receptors, TRH-R(1) and TRH-R(2).

Harder S, Lu X, Wang W, Buck F, Gershengorn MC, Bruhn TO. Harder S, et al. Among authors: gershengorn mc. Endocrinology. 2001 Mar;142(3):1188-94. doi: 10.1210/endo.142.3.8019. Endocrinology. 2001. PMID: 11181534

4

Synthesis and biology of new thyrotropin-releasing hormone (TRH) analogues.

Jain R, Singh J, Perlman JH, Gershengorn MC. Jain R, et al. Among authors: gershengorn mc. Bioorg Med Chem. 2002 Jan;10(1):189-94. doi: 10.1016/s0968-0896(01)00265-6. Bioorg Med Chem. 2002. PMID: 11738621

5

Conformationally restricted TRH analogues: constraining the pyroglutamate region.

Simpson JC, Ho C, Shands EF, Gershengorn MC, Marshall GR, Moeller KD. Simpson JC, et al. Among authors: gershengorn mc. Bioorg Med Chem. 2002 Feb;10(2):291-302. doi: 10.1016/s0968-0896(01)00287-5. Bioorg Med Chem. 2002. PMID: 11741778

6

Thyrotropin-releasing hormone receptors -- similarities and differences.

Sun Y, Lu X, Gershengorn MC. Sun Y, et al. Among authors: gershengorn mc. J Mol Endocrinol. 2003 Apr;30(2):87-97. doi: 10.1677/jme.0.0300087. J Mol Endocrinol. 2003. PMID: 12683933 Review.

7

Pharmacological studies of thyrotropin-releasing hormone (TRH) receptors from Xenopus laevis: is xTRHR3 a TRH receptor?

Lu X, Bidaud I, Ladram A, Gershengorn MC. Lu X, et al. Among authors: gershengorn mc. Endocrinology. 2003 May;144(5):1842-6. doi: 10.1210/en.2002-221074. Endocrinology. 2003. PMID: 12697690

8

A model of inverse agonist action at thyrotropin-releasing hormone receptor type 1: role of a conserved tryptophan in helix 6.

Lu X, Huang W, Worthington S, Drabik P, Osman R, Gershengorn MC. Lu X, et al. Among authors: gershengorn mc. Mol Pharmacol. 2004 Nov;66(5):1192-200. doi: 10.1124/mol.104.000349. Epub 2004 Aug 11. Mol Pharmacol. 2004. PMID: 15306657

9

Agonist-induced conformational changes in thyrotropin-releasing hormone receptor type I: disulfide cross-linking and molecular modeling approaches.

Huang W, Osman R, Gershengorn MC. Huang W, et al. Among authors: gershengorn mc. Biochemistry. 2005 Feb 22;44(7):2419-31. doi: 10.1021/bi048808+. Biochemistry. 2005. PMID: 15709754

10

Carboxyl tail cysteine mutants of the thyrotropin-releasing hormone receptor type 1 exhibit constitutive signaling: role of palmitoylation.

Du D, Raaka BM, Grimberg H, Lupu-Meiri M, Oron Y, Gershengorn MC. Du D, et al. Among authors: gershengorn mc. Mol Pharmacol. 2005 Jul;68(1):204-9. doi: 10.1124/mol.105.012641. Epub 2005 Apr 15. Mol Pharmacol. 2005. PMID: 15833733

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