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An interplay between hypervariable region 1 of the hepatitis C virus E2 glycoprotein, the scavenger receptor BI, and high-density lipoprotein promotes both enhancement of infection and protection against neutralizing antibodies.
Bartosch B, Verney G, Dreux M, Donot P, Morice Y, Penin F, Pawlotsky JM, Lavillette D, Cosset FL. Bartosch B, et al. Among authors: lavillette d. J Virol. 2005 Jul;79(13):8217-29. doi: 10.1128/JVI.79.13.8217-8229.2005. J Virol. 2005. PMID: 15956567 Free PMC article.
High density lipoprotein inhibits hepatitis C virus-neutralizing antibodies by stimulating cell entry via activation of the scavenger receptor BI.
Dreux M, Pietschmann T, Granier C, Voisset C, Ricard-Blum S, Mangeot PE, Keck Z, Foung S, Vu-Dac N, Dubuisson J, Bartenschlager R, Lavillette D, Cosset FL. Dreux M, et al. Among authors: lavillette d. J Biol Chem. 2006 Jul 7;281(27):18285-95. doi: 10.1074/jbc.M602706200. Epub 2006 May 4. J Biol Chem. 2006. PMID: 16675450 Free article.
Cell entry of enveloped viruses.
Cosset FL, Lavillette D. Cosset FL, et al. Among authors: lavillette d. Adv Genet. 2011;73:121-83. doi: 10.1016/B978-0-12-380860-8.00004-5. Adv Genet. 2011. PMID: 21310296 Free PMC article. Review.
The mechanism of HCV entry into host cells.
Douam F, Lavillette D, Cosset FL. Douam F, et al. Among authors: lavillette d. Prog Mol Biol Transl Sci. 2015;129:63-107. doi: 10.1016/bs.pmbts.2014.10.003. Epub 2014 Dec 12. Prog Mol Biol Transl Sci. 2015. PMID: 25595801 Review.
Human serum facilitates hepatitis C virus infection, and neutralizing responses inversely correlate with viral replication kinetics at the acute phase of hepatitis C virus infection.
Lavillette D, Morice Y, Germanidis G, Donot P, Soulier A, Pagkalos E, Sakellariou G, Intrator L, Bartosch B, Pawlotsky JM, Cosset FL. Lavillette D, et al. J Virol. 2005 May;79(10):6023-34. doi: 10.1128/JVI.79.10.6023-6034.2005. J Virol. 2005. PMID: 15857988 Free PMC article.
85 results