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A large-scale RNAi screen in human cells identifies new components of the p53 pathway.
Berns K, Hijmans EM, Mullenders J, Brummelkamp TR, Velds A, Heimerikx M, Kerkhoven RM, Madiredjo M, Nijkamp W, Weigelt B, Agami R, Ge W, Cavet G, Linsley PS, Beijersbergen RL, Bernards R. Berns K, et al. Among authors: kerkhoven rm. Nature. 2004 Mar 25;428(6981):431-7. doi: 10.1038/nature02371. Nature. 2004. PMID: 15042092
BRD7 is a candidate tumour suppressor gene required for p53 function.
Drost J, Mantovani F, Tocco F, Elkon R, Comel A, Holstege H, Kerkhoven R, Jonkers J, Voorhoeve PM, Agami R, Del Sal G. Drost J, et al. Nat Cell Biol. 2010 Apr;12(4):380-9. doi: 10.1038/ncb2038. Epub 2010 Mar 14. Nat Cell Biol. 2010. PMID: 20228809
Glucosylated hydroxymethyluracil, DNA base J, prevents transcriptional readthrough in Leishmania.
van Luenen HG, Farris C, Jan S, Genest PA, Tripathi P, Velds A, Kerkhoven RM, Nieuwland M, Haydock A, Ramasamy G, Vainio S, Heidebrecht T, Perrakis A, Pagie L, van Steensel B, Myler PJ, Borst P. van Luenen HG, et al. Among authors: kerkhoven rm. Cell. 2012 Aug 31;150(5):909-21. doi: 10.1016/j.cell.2012.07.030. Cell. 2012. PMID: 22939620 Free PMC article.
Gene expression profiling predicts clinical outcome of breast cancer.
van 't Veer LJ, Dai H, van de Vijver MJ, He YD, Hart AA, Mao M, Peterse HL, van der Kooy K, Marton MJ, Witteveen AT, Schreiber GJ, Kerkhoven RM, Roberts C, Linsley PS, Bernards R, Friend SH. van 't Veer LJ, et al. Among authors: kerkhoven rm. Nature. 2002 Jan 31;415(6871):530-6. doi: 10.1038/415530a. Nature. 2002. PMID: 11823860
The deubiquitinating enzyme USP1 regulates the Fanconi anemia pathway.
Nijman SM, Huang TT, Dirac AM, Brummelkamp TR, Kerkhoven RM, D'Andrea AD, Bernards R. Nijman SM, et al. Among authors: kerkhoven rm. Mol Cell. 2005 Feb 4;17(3):331-9. doi: 10.1016/j.molcel.2005.01.008. Mol Cell. 2005. PMID: 15694335 Free article.
72 results