Zhang J - Search Results

1

Brain distribution and efficacy as chemosensitizer of an oral formulation of PARP-1 inhibitor GPI 15427 in experimental models of CNS tumors.

Tentori L, Leonetti C, Scarsella M, Vergati M, Xu W, Calvin D, Morgan L, Tang Z, Woznizk K, Alemu C, Hoover R, Lapidus R, Zhang J, Graziani G. Tentori L, et al. Among authors: zhang j. Int J Oncol. 2005 Feb;26(2):415-22. Int J Oncol. 2005. PMID: 15645126

2

Systemic administration of GPI 15427, a novel poly(ADP-ribose) polymerase-1 inhibitor, increases the antitumor activity of temozolomide against intracranial melanoma, glioma, lymphoma.

Tentori L, Leonetti C, Scarsella M, D'Amati G, Vergati M, Portarena I, Xu W, Kalish V, Zupi G, Zhang J, Graziani G. Tentori L, et al. Among authors: zhang j. Clin Cancer Res. 2003 Nov 1;9(14):5370-9. Clin Cancer Res. 2003. PMID: 14614022

3

Poly(ADP-ribose) glycohydrolase inhibitor as chemosensitiser of malignant melanoma for temozolomide.

Tentori L, Leonetti C, Scarsella M, Muzi A, Vergati M, Forini O, Lacal PM, Ruffini F, Gold B, Li W, Zhang J, Graziani G. Tentori L, et al. Among authors: zhang j. Eur J Cancer. 2005 Dec;41(18):2948-57. doi: 10.1016/j.ejca.2005.08.027. Epub 2005 Nov 8. Eur J Cancer. 2005. PMID: 16288862

4

Inhibition of poly(ADP-ribose) polymerase prevents irinotecan-induced intestinal damage and enhances irinotecan/temozolomide efficacy against colon carcinoma.

Tentori L, Leonetti C, Scarsella M, Muzi A, Mazzon E, Vergati M, Forini O, Lapidus R, Xu W, Dorio AS, Zhang J, Cuzzocrea S, Graziani G. Tentori L, et al. Among authors: zhang j. FASEB J. 2006 Aug;20(10):1709-11. doi: 10.1096/fj.06-5916fje. Epub 2006 Jun 29. FASEB J. 2006. PMID: 16809434

5

Poly(ADP-ribose) polymerase (PARP) inhibition or PARP-1 gene deletion reduces angiogenesis.

Tentori L, Lacal PM, Muzi A, Dorio AS, Leonetti C, Scarsella M, Ruffini F, Xu W, Min W, Stoppacciaro A, Colarossi C, Wang ZQ, Zhang J, Graziani G. Tentori L, et al. Among authors: zhang j. Eur J Cancer. 2007 Sep;43(14):2124-33. doi: 10.1016/j.ejca.2007.07.010. Epub 2007 Aug 21. Eur J Cancer. 2007. PMID: 17714938

6

Pharmacological inhibition of poly(ADP-ribose) polymerase activity down-regulates the expression of syndecan-4 and Id-1 in endothelial cells.

Lacal PM, Tentori L, Muzi A, Ruffini F, Dorio AS, Xu W, Arcelli D, Zhang J, Graziani G. Lacal PM, et al. Among authors: zhang j. Int J Oncol. 2009 Mar;34(3):861-72. doi: 10.3892/ijo_00000213. Int J Oncol. 2009. PMID: 19212692

7

PARP-1 inhibition to treat cancer, ischemia, inflammation.

Graziani G, Battaini F, Zhang J. Graziani G, et al. Among authors: zhang j. Pharmacol Res. 2005 Jul;52(1):1-4. doi: 10.1016/j.phrs.2005.02.007. Pharmacol Res. 2005. PMID: 15911328 No abstract available.

8

Stable depletion of poly (ADP-ribose) polymerase-1 reduces in vivo melanoma growth and increases chemosensitivity.

Tentori L, Muzi A, Dorio AS, Bultrini S, Mazzon E, Lacal PM, Shah GM, Zhang J, Navarra P, Nocentini G, Cuzzocrea S, Graziani G. Tentori L, et al. Among authors: zhang j. Eur J Cancer. 2008 Jun;44(9):1302-14. doi: 10.1016/j.ejca.2008.03.019. Epub 2008 Apr 24. Eur J Cancer. 2008. PMID: 18440222

9

Head and neck cancer radiosensitization by the novel poly(ADP-ribose) polymerase inhibitor GPI-15427.

Khan K, Araki K, Wang D, Li G, Li X, Zhang J, Xu W, Hoover RK, Lauter S, O'Malley B Jr, Lapidus RG, Li D. Khan K, et al. Among authors: zhang j. Head Neck. 2010 Mar;32(3):381-91. doi: 10.1002/hed.21195. Head Neck. 2010. PMID: 19672867

10

Treatment with PARP-1 inhibitors, GPI 15427 or GPI 16539, ameliorates intestinal damage in rat models of colitis and shock.

Di Paola R, Mazzon E, Xu W, Genovese T, Ferrraris D, Muià C, Crisafulli C, Zhang J, Cuzzocrea S. Di Paola R, et al. Among authors: zhang j. Eur J Pharmacol. 2005 Dec 19;527(1-3):163-71. doi: 10.1016/j.ejphar.2005.09.055. Epub 2005 Nov 28. Eur J Pharmacol. 2005. PMID: 16310767

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