Chen Z - Search Results

1

The p53 regulatory gene MDM2 is a direct transcriptional target of MYCN in neuroblastoma.

Slack A, Chen Z, Tonelli R, Pule M, Hunt L, Pession A, Shohet JM. Slack A, et al. Among authors: chen z. Proc Natl Acad Sci U S A. 2005 Jan 18;102(3):731-6. doi: 10.1073/pnas.0405495102. Epub 2005 Jan 11. Proc Natl Acad Sci U S A. 2005. PMID: 15644444 Free PMC article.

2

MDM2 inhibition sensitizes neuroblastoma to chemotherapy-induced apoptotic cell death.

Barbieri E, Mehta P, Chen Z, Zhang L, Slack A, Berg S, Shohet JM. Barbieri E, et al. Among authors: chen z. Mol Cancer Ther. 2006 Sep;5(9):2358-65. doi: 10.1158/1535-7163.MCT-06-0305. Mol Cancer Ther. 2006. PMID: 16985070

3

MYCN-directed centrosome amplification requires MDM2-mediated suppression of p53 activity in neuroblastoma cells.

Slack AD, Chen Z, Ludwig AD, Hicks J, Shohet JM. Slack AD, et al. Among authors: chen z. Cancer Res. 2007 Mar 15;67(6):2448-55. doi: 10.1158/0008-5472.CAN-06-1661. Cancer Res. 2007. PMID: 17363562

4

Mdm2 deficiency suppresses MYCN-Driven neuroblastoma tumorigenesis in vivo.

Chen Z, Lin Y, Barbieri E, Burlingame S, Hicks J, Ludwig A, Shohet JM. Chen Z, et al. Neoplasia. 2009 Aug;11(8):753-62. doi: 10.1593/neo.09466. Neoplasia. 2009. PMID: 19649205 Free PMC article.

5

Effect of MDM2 and vascular endothelial growth factor inhibition on tumor angiogenesis and metastasis in neuroblastoma.

Patterson DM, Gao D, Trahan DN, Johnson BA, Ludwig A, Barbieri E, Chen Z, Diaz-Miron J, Vassilev L, Shohet JM, Kim ES. Patterson DM, et al. Among authors: chen z. Angiogenesis. 2011 Sep;14(3):255-66. doi: 10.1007/s10456-011-9210-8. Epub 2011 Apr 12. Angiogenesis. 2011. PMID: 21484514

6

A genome-wide search for promoters that respond to increased MYCN reveals both new oncogenic and tumor suppressor microRNAs associated with aggressive neuroblastoma.

Shohet JM, Ghosh R, Coarfa C, Ludwig A, Benham AL, Chen Z, Patterson DM, Barbieri E, Mestdagh P, Sikorski DN, Milosavljevic A, Kim ES, Gunaratne PH. Shohet JM, et al. Among authors: chen z. Cancer Res. 2011 Jun 1;71(11):3841-51. doi: 10.1158/0008-5472.CAN-10-4391. Epub 2011 Apr 15. Cancer Res. 2011. PMID: 21498633

7

G-CSF receptor positive neuroblastoma subpopulations are enriched in chemotherapy-resistant or relapsed tumors and are highly tumorigenic.

Hsu DM, Agarwal S, Benham A, Coarfa C, Trahan DN, Chen Z, Stowers PN, Courtney AN, Lakoma A, Barbieri E, Metelitsa LS, Gunaratne P, Kim ES, Shohet JM. Hsu DM, et al. Among authors: chen z. Cancer Res. 2013 Jul 1;73(13):4134-46. doi: 10.1158/0008-5472.CAN-12-4056. Epub 2013 May 16. Cancer Res. 2013. PMID: 23687340 Free PMC article.

8

Histone chaperone CHAF1A inhibits differentiation and promotes aggressive neuroblastoma.

Barbieri E, De Preter K, Capasso M, Chen Z, Hsu DM, Tonini GP, Lefever S, Hicks J, Versteeg R, Pession A, Speleman F, Kim ES, Shohet JM. Barbieri E, et al. Among authors: chen z. Cancer Res. 2014 Feb 1;74(3):765-74. doi: 10.1158/0008-5472.CAN-13-1315. Epub 2013 Dec 12. Cancer Res. 2014. PMID: 24335960

9

A p53 drug response signature identifies prognostic genes in high-risk neuroblastoma.

Barbieri E, De Preter K, Capasso M, Johansson P, Man TK, Chen Z, Stowers P, Tonini GP, Speleman F, Shohet JM. Barbieri E, et al. Among authors: chen z. PLoS One. 2013 Nov 19;8(11):e79843. doi: 10.1371/journal.pone.0079843. eCollection 2013. PLoS One. 2013. PMID: 24348903 Free PMC article.

10

G-CSF Promotes Neuroblastoma Tumorigenicity and Metastasis via STAT3-Dependent Cancer Stem Cell Activation.

Agarwal S, Lakoma A, Chen Z, Hicks J, Metelitsa LS, Kim ES, Shohet JM. Agarwal S, et al. Among authors: chen z. Cancer Res. 2015 Jun 15;75(12):2566-79. doi: 10.1158/0008-5472.CAN-14-2946. Epub 2015 Apr 23. Cancer Res. 2015. PMID: 25908586 Free PMC article.

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