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Very early treatment with infliximab in addition to methotrexate in early, poor-prognosis rheumatoid arthritis reduces magnetic resonance imaging evidence of synovitis and damage, with sustained benefit after infliximab withdrawal: results from a twelve-month randomized, double-blind, placebo-controlled trial.
Quinn MA, Conaghan PG, O'Connor PJ, Karim Z, Greenstein A, Brown A, Brown C, Fraser A, Jarret S, Emery P. Quinn MA, et al. Among authors: brown c, brown a. Arthritis Rheum. 2005 Jan;52(1):27-35. doi: 10.1002/art.20712. Arthritis Rheum. 2005. PMID: 15641102 Free article. Clinical Trial.
Expanding Conjugate Space of RNAi Therapeutics: Ligand at the 3' End of the Antisense Strand Achieves Uncompromised In Vivo Potency and Efficacy and Reveals Interactions with the Argonaute-2 PAZ Domain.
Das RS, Datta D, Brown CR, Gilbert JA, Chan A, Willoughby J, Gupta S, Kim M, Degaonkar R, Racie T, Lei L, Schlegel MK, Castoreno A, Charisse K, Rajeev KG, Egli M, Manoharan M. Das RS, et al. Among authors: brown cr. J Med Chem. 2025 Feb 3. doi: 10.1021/acs.jmedchem.4c02250. Online ahead of print. J Med Chem. 2025. PMID: 39899704
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