Orfi L - Search Results

1

Acid-base profiling of imatinib (gleevec) and its fragments.

Szakács Z, Béni S, Varga Z, Orfi L, Kéri G, Noszál B. Szakács Z, et al. Among authors: orfi l. J Med Chem. 2005 Jan 13;48(1):249-55. doi: 10.1021/jm049546c. J Med Chem. 2005. PMID: 15634018

2

Determination of human serum alpha1-acid glycoprotein and albumin binding of various marketed and preclinical kinase inhibitors.

Zsila F, Fitos I, Bencze G, Kéri G, Orfi L. Zsila F, et al. Among authors: orfi l. Curr Med Chem. 2009;16(16):1964-77. doi: 10.2174/092986709788682191. Curr Med Chem. 2009. PMID: 19519376 Review.

3

Small-molecule inhibitors of NADPH oxidase 4.

Borbély G, Szabadkai I, Horváth Z, Markó P, Varga Z, Breza N, Baska F, Vántus T, Huszár M, Geiszt M, Hunyady L, Buday L, Orfi L, Kéri G. Borbély G, et al. Among authors: orfi l. J Med Chem. 2010 Sep 23;53(18):6758-62. doi: 10.1021/jm1004368. J Med Chem. 2010. PMID: 20731357

4

Synthesis and evaluation of phosphorus containing, specific CDK9/CycT1 inhibitors.

Németh G, Greff Z, Sipos A, Varga Z, Székely R, Sebestyén M, Jászay Z, Béni S, Nemes Z, Pirat JL, Volle JN, Virieux D, Gyuris Á, Kelemenics K, Ay E, Minarovits J, Szathmary S, Kéri G, Orfi L. Németh G, et al. Among authors: orfi l. J Med Chem. 2014 May 22;57(10):3939-65. doi: 10.1021/jm401742r. Epub 2014 May 2. J Med Chem. 2014. PMID: 24742150

5

Comparison of predictive ability of water solubility QSPR models generated by MLR, PLS and ANN methods.

Erös D, Kéri G, Kövesdi I, Szántai-Kis C, Mészáros G, Orfi L. Erös D, et al. Among authors: orfi l. Mini Rev Med Chem. 2004 Feb;4(2):167-77. doi: 10.2174/1389557043487466. Mini Rev Med Chem. 2004. PMID: 14965289

6

Improved, high yield synthesis of 3H-quinazolin-4-ones, the key intermediates of recently developed drugs.

Orfi L, Wáczek F, Pató J, Varga I, Hegymegi-Barakonyi B, Houghten RA, Kéri G. Orfi L, et al. Curr Med Chem. 2004 Oct;11(19):2549-53. doi: 10.2174/0929867043364423. Curr Med Chem. 2004. PMID: 15544462

7

Design and synthesis of new imidazo[1,2-a]pyridine and imidazo[1,2-a]pyrazine derivatives with antiproliferative activity against melanoma cells.

Garamvölgyi R, Dobos J, Sipos A, Boros S, Illyés E, Baska F, Kékesi L, Szabadkai I, Szántai-Kis C, Kéri G, Őrfi L. Garamvölgyi R, et al. Among authors: orfi l. Eur J Med Chem. 2016 Jan 27;108:623-643. doi: 10.1016/j.ejmech.2015.12.001. Epub 2015 Dec 12. Eur J Med Chem. 2016. PMID: 26724730

8

Interaction of tyrosine kinase inhibitors with the human multidrug transporter proteins, MDR1 and MRP1.

Hegedus T, Orfi L, Seprodi A, Váradi A, Sarkadi B, Kéri G. Hegedus T, et al. Among authors: orfi l. Biochim Biophys Acta. 2002 Jul 18;1587(2-3):318-25. doi: 10.1016/s0925-4439(02)00095-9. Biochim Biophys Acta. 2002. PMID: 12084474 Free article. Review.

9

A closer look at the structure of sterically stabilized liposomes: a small-angle X-ray scattering study.

Varga Z, Berényi S, Szokol B, Orfi L, Kéri G, Peták I, Hoell A, Bóta A. Varga Z, et al. Among authors: orfi l. J Phys Chem B. 2010 May 27;114(20):6850-4. doi: 10.1021/jp9109207. J Phys Chem B. 2010. PMID: 20429570

10

Synthesis and biological evaluation of novel pyrido[2,3-b]pyrazines inhibiting both erlotinib-sensitive and erlotinib-resistant cell lines.

Kékesi L, Sipos A, Németh G, Pató J, Breza N, Baska F, Őrfi L, Kéri G. Kékesi L, et al. Among authors: orfi l. Bioorg Med Chem Lett. 2013 Nov 15;23(22):6152-5. doi: 10.1016/j.bmcl.2013.09.005. Epub 2013 Sep 8. Bioorg Med Chem Lett. 2013. PMID: 24095095

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