Cole PA - Search Results

1

Histone demethylation mediated by the nuclear amine oxidase homolog LSD1.

Shi Y, Lan F, Matson C, Mulligan P, Whetstine JR, Cole PA, Casero RA, Shi Y. Shi Y, et al. Among authors: cole pa. Cell. 2004 Dec 29;119(7):941-53. doi: 10.1016/j.cell.2004.12.012. Cell. 2004. PMID: 15620353 Free article.

2

A selective phenelzine analogue inhibitor of histone demethylase LSD1.

Prusevich P, Kalin JH, Ming SA, Basso M, Givens J, Li X, Hu J, Taylor MS, Cieniewicz AM, Hsiao PY, Huang R, Roberson H, Adejola N, Avery LB, Casero RA Jr, Taverna SD, Qian J, Tackett AJ, Ratan RR, McDonald OG, Feinberg AP, Cole PA. Prusevich P, et al. Among authors: cole pa. ACS Chem Biol. 2014 Jun 20;9(6):1284-93. doi: 10.1021/cb500018s. Epub 2014 Apr 7. ACS Chem Biol. 2014. PMID: 24707965 Free PMC article.

3

Time-Resolved Analysis Reveals Rapid Dynamics and Broad Scope of the CBP/p300 Acetylome.

Weinert BT, Narita T, Satpathy S, Srinivasan B, Hansen BK, Schölz C, Hamilton WB, Zucconi BE, Wang WW, Liu WR, Brickman JM, Kesicki EA, Lai A, Bromberg KD, Cole PA, Choudhary C. Weinert BT, et al. Among authors: cole pa. Cell. 2018 Jun 28;174(1):231-244.e12. doi: 10.1016/j.cell.2018.04.033. Epub 2018 May 24. Cell. 2018. PMID: 29804834 Free PMC article.

4

Re-programing Chromatin with a Bifunctional LSD1/HDAC Inhibitor Induces Therapeutic Differentiation in DIPG.

Anastas JN, Zee BM, Kalin JH, Kim M, Guo R, Alexandrescu S, Blanco MA, Giera S, Gillespie SM, Das J, Wu M, Nocco S, Bonal DM, Nguyen QD, Suva ML, Bernstein BE, Alani R, Golub TR, Cole PA, Filbin MG, Shi Y. Anastas JN, et al. Among authors: cole pa. Cancer Cell. 2019 Nov 11;36(5):528-544.e10. doi: 10.1016/j.ccell.2019.09.005. Epub 2019 Oct 17. Cancer Cell. 2019. PMID: 31631026 Free article.

5

Mechanism of Crosstalk between the LSD1 Demethylase and HDAC1 Deacetylase in the CoREST Complex.

Song Y, Dagil L, Fairall L, Robertson N, Wu M, Ragan TJ, Savva CG, Saleh A, Morone N, Kunze MBA, Jamieson AG, Cole PA, Hansen DF, Schwabe JWR. Song Y, et al. Among authors: cole pa. Cell Rep. 2020 Feb 25;30(8):2699-2711.e8. doi: 10.1016/j.celrep.2020.01.091. Cell Rep. 2020. PMID: 32101746 Free PMC article.

6

HATs off: selective synthetic inhibitors of the histone acetyltransferases p300 and PCAF.

Lau OD, Kundu TK, Soccio RE, Ait-Si-Ali S, Khalil EM, Vassilev A, Wolffe AP, Nakatani Y, Roeder RG, Cole PA. Lau OD, et al. Among authors: cole pa. Mol Cell. 2000 Mar;5(3):589-95. doi: 10.1016/s1097-2765(00)80452-9. Mol Cell. 2000. PMID: 10882143 Free article.

7

Mechanistic analysis of a suicide inactivator of histone demethylase LSD1.

Szewczuk LM, Culhane JC, Yang M, Majumdar A, Yu H, Cole PA. Szewczuk LM, et al. Among authors: cole pa. Biochemistry. 2007 Jun 12;46(23):6892-902. doi: 10.1021/bi700414b. Epub 2007 May 19. Biochemistry. 2007. PMID: 17511474 Free PMC article.

8

Structural basis of histone demethylation by LSD1 revealed by suicide inactivation.

Yang M, Culhane JC, Szewczuk LM, Gocke CB, Brautigam CA, Tomchick DR, Machius M, Cole PA, Yu H. Yang M, et al. Among authors: cole pa. Nat Struct Mol Biol. 2007 Jun;14(6):535-9. doi: 10.1038/nsmb1255. Epub 2007 May 27. Nat Struct Mol Biol. 2007. PMID: 17529991

9

Structural basis for the inhibition of the LSD1 histone demethylase by the antidepressant trans-2-phenylcyclopropylamine.

Yang M, Culhane JC, Szewczuk LM, Jalili P, Ball HL, Machius M, Cole PA, Yu H. Yang M, et al. Among authors: cole pa. Biochemistry. 2007 Jul 10;46(27):8058-65. doi: 10.1021/bi700664y. Epub 2007 Jun 15. Biochemistry. 2007. PMID: 17569509

10

LSD1 and the chemistry of histone demethylation.

Culhane JC, Cole PA. Culhane JC, et al. Among authors: cole pa. Curr Opin Chem Biol. 2007 Oct;11(5):561-8. doi: 10.1016/j.cbpa.2007.07.014. Epub 2007 Sep 11. Curr Opin Chem Biol. 2007. PMID: 17851108 Free PMC article. Review.

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