Kane WH - Search Results

1

Human platelets contain forms of factor V in disulfide-linkage with multimerin.

Hayward CP, Fuller N, Zheng S, Adam F, Jeimy SB, Horsewood I, Quinn-Allen MA, Kane WH. Hayward CP, et al. Among authors: kane wh. Thromb Haemost. 2004 Dec;92(6):1349-57. doi: 10.1160/TH03-02-0123. Thromb Haemost. 2004. PMID: 15583744

2

Identification of the MMRN1 binding region within the C2 domain of human factor V.

Jeimy SB, Woram RA, Fuller N, Quinn-Allen MA, Nicolaes GA, Dahlbäck B, Kane WH, Hayward CP. Jeimy SB, et al. Among authors: kane wh. J Biol Chem. 2004 Dec 3;279(49):51466-71. doi: 10.1074/jbc.M409866200. Epub 2004 Sep 27. J Biol Chem. 2004. PMID: 15452129 Free article.

3

Location of the multimerin 1 binding site in coagulation factor V: an update.

Jeimy SB, Quinn-Allen MA, Fuller N, Kane WH, Hayward CP. Jeimy SB, et al. Among authors: kane wh. Thromb Res. 2008;123(2):352-4. doi: 10.1016/j.thromres.2008.03.016. Epub 2008 May 2. Thromb Res. 2008. PMID: 18452976 Free PMC article.

4

An autosomal dominant, qualitative platelet disorder associated with multimerin deficiency, abnormalities in platelet factor V, thrombospondin, von Willebrand factor, and fibrinogen and an epinephrine aggregation defect.

Hayward CP, Rivard GE, Kane WH, Drouin J, Zheng S, Moore JC, Kelton JG. Hayward CP, et al. Among authors: kane wh. Blood. 1996 Jun 15;87(12):4967-78. Blood. 1996. PMID: 8652809 Free article.

5

Mutation of hydrophobic residues in the factor Va C1 and C2 domains blocks membrane-dependent prothrombin activation.

Peng W, Quinn-Allen MA, Kane WH. Peng W, et al. Among authors: kane wh. J Thromb Haemost. 2005 Feb;3(2):351-4. doi: 10.1111/j.1538-7836.2004.01083.x. J Thromb Haemost. 2005. PMID: 15670043 Free article.

6

The factor V C1 domain is involved in membrane binding: identification of functionally important amino acid residues within the C1 domain of factor V using alanine scanning mutagenesis.

Saleh M, Peng W, Quinn-Allen MA, Macedo-Ribeiro S, Fuentes-Prior P, Bode W, Kane WH. Saleh M, et al. Among authors: kane wh. Thromb Haemost. 2004 Jan;91(1):16-27. doi: 10.1160/TH03-04-0222. Thromb Haemost. 2004. PMID: 14691564

7

Studies of a second family with the Quebec platelet disorder: evidence that the degradation of the alpha-granule membrane and its soluble contents are not secondary to a defect in targeting proteins to alpha-granules.

Hayward CP, Cramer EM, Kane WH, Zheng S, Bouchard M, Massé JM, Rivard GE. Hayward CP, et al. Among authors: kane wh. Blood. 1997 Feb 15;89(4):1243-53. Blood. 1997. PMID: 9028947 Free article.

8

The phosphatidylserine binding site of the factor Va C2 domain accounts for membrane binding but does not contribute to the assembly or activity of a human factor Xa-factor Va complex.

Majumder R, Quinn-Allen MA, Kane WH, Lentz BR. Majumder R, et al. Among authors: kane wh. Biochemistry. 2005 Jan 18;44(2):711-8. doi: 10.1021/bi047962t. Biochemistry. 2005. PMID: 15641797

9

A phosphatidylserine binding site in factor Va C1 domain regulates both assembly and activity of the prothrombinase complex.

Majumder R, Quinn-Allen MA, Kane WH, Lentz BR. Majumder R, et al. Among authors: kane wh. Blood. 2008 Oct 1;112(7):2795-802. doi: 10.1182/blood-2008-02-138941. Epub 2008 Jun 27. Blood. 2008. PMID: 18587009 Free PMC article.

10

Trp2063 and Trp2064 in the factor Va C2 domain are required for high-affinity binding to phospholipid membranes but not for assembly of the prothrombinase complex.

Peng W, Quinn-Allen MA, Kim SW, Alexander KA, Kane WH. Peng W, et al. Among authors: kane wh. Biochemistry. 2004 Apr 13;43(14):4385-93. doi: 10.1021/bi035763o. Biochemistry. 2004. PMID: 15065883

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