Roth BL - Search Results

1

Synthesis and receptor assay of aromatic-ethynyl-aromatic derivatives with potent mGluR5 antagonist activity.

Alagille D, Baldwin RM, Roth BL, Wroblewski JT, Grajkowska E, Tamagnan GD. Alagille D, et al. Among authors: roth bl. Bioorg Med Chem. 2005 Jan 3;13(1):197-209. doi: 10.1016/j.bmc.2004.09.042. Bioorg Med Chem. 2005. PMID: 15582465

2

Synthesis of potent and selective dopamine D(4) antagonists as candidate radioligands.

Huang Y, Kegeles LS, Bae S, Hwang D, Roth BL, Savage JE, Laruelle M. Huang Y, et al. Among authors: roth bl. Bioorg Med Chem Lett. 2001 Jun 4;11(11):1375-7. doi: 10.1016/s0960-894x(01)00241-4. Bioorg Med Chem Lett. 2001. PMID: 11378358

3

L-homocysteine sulfinic acid and other acidic homocysteine derivatives are potent and selective metabotropic glutamate receptor agonists.

Shi Q, Savage JE, Hufeisen SJ, Rauser L, Grajkowska E, Ernsberger P, Wroblewski JT, Nadeau JH, Roth BL. Shi Q, et al. Among authors: roth bl. J Pharmacol Exp Ther. 2003 Apr;305(1):131-42. doi: 10.1124/jpet.102.047092. J Pharmacol Exp Ther. 2003. PMID: 12649361

4

Ring substituted analogues of 5-aminomethyl-10,11-dihydro-dibenzo[a,d]cycloheptene (AMDH): potential modes of binding to the 5-HT(2A) receptor.

Peddi S, Roth BL, Glennon RA, Westkaemper RB. Peddi S, et al. Among authors: roth bl. Bioorg Med Chem Lett. 2003 Aug 4;13(15):2565-8. doi: 10.1016/s0960-894x(03)00504-3. Bioorg Med Chem Lett. 2003. PMID: 12852967

5

L-homocysteine sulfinic acid and L-homocysteic acid stimulate phosphoinositide hydrolysis in rat cortical neurons.

Shi Q, Hufeisen SJ, Wroblewski JT, Nadeau JH, Roth BL. Shi Q, et al. Among authors: roth bl. Ann N Y Acad Sci. 2003 Nov;1003:461-3. doi: 10.1196/annals.1300.054. Ann N Y Acad Sci. 2003. PMID: 14684489 No abstract available.

6

1,2,3,4-tetrahydrocarbazoles as 5-HT6 serotonin receptor ligands.

Chang-Fong J, Rangisetty JB, Dukat M, Setola V, Raffay T, Roth B, Glennon RA. Chang-Fong J, et al. Bioorg Med Chem Lett. 2004 Apr 19;14(8):1961-4. doi: 10.1016/j.bmcl.2004.01.071. Bioorg Med Chem Lett. 2004. PMID: 15050637

7

Functionalization at position 3 of the phenyl ring of the potent mGluR5 noncompetitive antagonists MPEP.

Alagille D, Baldwin RM, Roth BL, Wroblewski JT, Grajkowska E, Tamagnan GD. Alagille D, et al. Among authors: roth bl. Bioorg Med Chem Lett. 2005 Feb 15;15(4):945-9. doi: 10.1016/j.bmcl.2004.12.047. Bioorg Med Chem Lett. 2005. PMID: 15686891

8

1-(1-Naphthyl)piperazine as a novel template for 5-HT6 serotonin receptor ligands.

Lee M, Rangisetty JB, Pullagurla MR, Dukat M, Setola V, Roth BL, Glennon RA. Lee M, et al. Among authors: roth bl. Bioorg Med Chem Lett. 2005 Mar 15;15(6):1707-11. doi: 10.1016/j.bmcl.2005.01.031. Bioorg Med Chem Lett. 2005. PMID: 15745826

9

Synthesis of potent and selective serotonin 5-HT1B receptor ligands.

Huang Y, Bae SA, Roth BL, Laruelle M. Huang Y, et al. Among authors: roth bl. Bioorg Med Chem Lett. 2005 Nov 1;15(21):4786-9. doi: 10.1016/j.bmcl.2005.07.024. Bioorg Med Chem Lett. 2005. PMID: 16143528

10

Synthesis and structure-activity relationships of 3-[(2-methyl-1,3-thiazol-4-yl)ethynyl]pyridine analogues as potent, noncompetitive metabotropic glutamate receptor subtype 5 antagonists; search for cocaine medications.

Iso Y, Grajkowska E, Wroblewski JT, Davis J, Goeders NE, Johnson KM, Sanker S, Roth BL, Tueckmantel W, Kozikowski AP. Iso Y, et al. Among authors: roth bl. J Med Chem. 2006 Feb 9;49(3):1080-100. doi: 10.1021/jm050570f. J Med Chem. 2006. PMID: 16451073

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