Tenev T - Search Results

1

IAPs are functionally non-equivalent and regulate effector caspases through distinct mechanisms.

Tenev T, Zachariou A, Wilson R, Ditzel M, Meier P. Tenev T, et al. Nat Cell Biol. 2005 Jan;7(1):70-7. doi: 10.1038/ncb1204. Epub 2004 Dec 5. Nat Cell Biol. 2005. PMID: 15580265

2

Jafrac2 is an IAP antagonist that promotes cell death by liberating Dronc from DIAP1.

Tenev T, Zachariou A, Wilson R, Paul A, Meier P. Tenev T, et al. EMBO J. 2002 Oct 1;21(19):5118-29. doi: 10.1093/emboj/cdf530. EMBO J. 2002. PMID: 12356728 Free PMC article.

3

Degradation of DIAP1 by the N-end rule pathway is essential for regulating apoptosis.

Ditzel M, Wilson R, Tenev T, Zachariou A, Paul A, Deas E, Meier P. Ditzel M, et al. Among authors: tenev t. Nat Cell Biol. 2003 May;5(5):467-73. doi: 10.1038/ncb984. Nat Cell Biol. 2003. PMID: 12692559

4

IAP-antagonists exhibit non-redundant modes of action through differential DIAP1 binding.

Zachariou A, Tenev T, Goyal L, Agapite J, Steller H, Meier P. Zachariou A, et al. Among authors: tenev t. EMBO J. 2003 Dec 15;22(24):6642-52. doi: 10.1093/emboj/cdg617. EMBO J. 2003. PMID: 14657035 Free PMC article.

5

Systematic in vivo RNAi analysis of putative components of the Drosophila cell death machinery.

Leulier F, Ribeiro PS, Palmer E, Tenev T, Takahashi K, Robertson D, Zachariou A, Pichaud F, Ueda R, Meier P. Leulier F, et al. Among authors: tenev t. Cell Death Differ. 2006 Oct;13(10):1663-74. doi: 10.1038/sj.cdd.4401868. Epub 2006 Feb 17. Cell Death Differ. 2006. PMID: 16485033

6

The antiapoptotic activity of insect IAPs requires activation by an evolutionarily conserved mechanism.

Tenev T, Ditzel M, Zachariou A, Meier P. Tenev T, et al. Cell Death Differ. 2007 Jun;14(6):1191-201. doi: 10.1038/sj.cdd.4402118. Epub 2007 Mar 9. Cell Death Differ. 2007. PMID: 17347664

7

DIAP2 functions as a mechanism-based regulator of drICE that contributes to the caspase activity threshold in living cells.

Ribeiro PS, Kuranaga E, Tenev T, Leulier F, Miura M, Meier P. Ribeiro PS, et al. Among authors: tenev t. J Cell Biol. 2007 Dec 31;179(7):1467-80. doi: 10.1083/jcb.200706027. J Cell Biol. 2007. PMID: 18166655 Free PMC article.

8

PIMS modulates immune tolerance by negatively regulating Drosophila innate immune signaling.

Lhocine N, Ribeiro PS, Buchon N, Wepf A, Wilson R, Tenev T, Lemaitre B, Gstaiger M, Meier P, Leulier F. Lhocine N, et al. Among authors: tenev t. Cell Host Microbe. 2008 Aug 14;4(2):147-58. doi: 10.1016/j.chom.2008.07.004. Cell Host Microbe. 2008. PMID: 18692774 Free article.

9

IAPs contain an evolutionarily conserved ubiquitin-binding domain that regulates NF-kappaB as well as cell survival and oncogenesis.

Gyrd-Hansen M, Darding M, Miasari M, Santoro MM, Zender L, Xue W, Tenev T, da Fonseca PC, Zvelebil M, Bujnicki JM, Lowe S, Silke J, Meier P. Gyrd-Hansen M, et al. Among authors: tenev t. Nat Cell Biol. 2008 Nov;10(11):1309-17. doi: 10.1038/ncb1789. Epub 2008 Oct 19. Nat Cell Biol. 2008. PMID: 18931663 Free PMC article.

10

Inactivation of effector caspases through nondegradative polyubiquitylation.

Ditzel M, Broemer M, Tenev T, Bolduc C, Lee TV, Rigbolt KT, Elliott R, Zvelebil M, Blagoev B, Bergmann A, Meier P. Ditzel M, et al. Among authors: tenev t. Mol Cell. 2008 Nov 21;32(4):540-53. doi: 10.1016/j.molcel.2008.09.025. Mol Cell. 2008. PMID: 19026784 Free PMC article.

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