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Cyclohexylcarbamic acid 3'- or 4'-substituted biphenyl-3-yl esters as fatty acid amide hydrolase inhibitors: synthesis, quantitative structure-activity relationships, and molecular modeling studies.
Mor M, Rivara S, Lodola A, Plazzi PV, Tarzia G, Duranti A, Tontini A, Piersanti G, Kathuria S, Piomelli D. Mor M, et al. Among authors: tontini a. J Med Chem. 2004 Oct 7;47(21):4998-5008. doi: 10.1021/jm031140x. J Med Chem. 2004. PMID: 15456244 Free article.
N-(2-oxo-3-oxetanyl)carbamic acid esters as N-acylethanolamine acid amidase inhibitors: synthesis and structure-activity and structure-property relationships.
Duranti A, Tontini A, Antonietti F, Vacondio F, Fioni A, Silva C, Lodola A, Rivara S, Solorzano C, Piomelli D, Tarzia G, Mor M. Duranti A, et al. Among authors: tontini a. J Med Chem. 2012 May 24;55(10):4824-36. doi: 10.1021/jm300349j. Epub 2012 May 10. J Med Chem. 2012. PMID: 22515328 Free article.
Pharmacological profile of the selective FAAH inhibitor KDS-4103 (URB597).
Piomelli D, Tarzia G, Duranti A, Tontini A, Mor M, Compton TR, Dasse O, Monaghan EP, Parrott JA, Putman D. Piomelli D, et al. Among authors: tontini a. CNS Drug Rev. 2006 Spring;12(1):21-38. doi: 10.1111/j.1527-3458.2006.00021.x. CNS Drug Rev. 2006. PMID: 16834756 Free PMC article. Review.
The fatty acid amide hydrolase inhibitor URB597 (cyclohexylcarbamic acid 3'-carbamoylbiphenyl-3-yl ester) reduces neuropathic pain after oral administration in mice.
Russo R, Loverme J, La Rana G, Compton TR, Parrott J, Duranti A, Tontini A, Mor M, Tarzia G, Calignano A, Piomelli D. Russo R, et al. Among authors: tontini a. J Pharmacol Exp Ther. 2007 Jul;322(1):236-42. doi: 10.1124/jpet.107.119941. Epub 2007 Apr 5. J Pharmacol Exp Ther. 2007. PMID: 17412883 Free article.
48 results