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1H NMR structure and biological studies of the His23-->Cys mutant nucleocapsid protein of HIV-1 indicate that the conformation of the first zinc finger is critical for virus infectivity.
Déméné H, Dong CZ, Ottmann M, Rouyez MC, Jullian N, Morellet N, Mely Y, Darlix JL, Fournié-Zaluski MC, Saragosti S, et al. Déméné H, et al. Among authors: morellet n. Biochemistry. 1994 Oct 4;33(39):11707-16. doi: 10.1021/bi00205a006. Biochemistry. 1994. PMID: 7918387
Spatial proximity of the HIV-1 nucleocapsid protein zinc fingers investigated by time-resolved fluorescence and fluorescence resonance energy transfer.
Mély Y, Jullian N, Morellet N, De Rocquigny H, Dong CZ, Piémont E, Roques BP, Gérard D. Mély Y, et al. Among authors: morellet n. Biochemistry. 1994 Oct 11;33(40):12085-91. doi: 10.1021/bi00206a011. Biochemistry. 1994. PMID: 7918429
Whereas the folded structures of the finger motifs were in good agreement, discrepancies existed concerning their spatial relationship since the fingers were found either close to each other [Morellet, N., Jullian, N., De Rocquigny, H., Maigret, B., Darlix, J …
Whereas the folded structures of the finger motifs were in good agreement, discrepancies existed concerning their spatial relationship since …
Structural and dynamic characterization of the aromatic amino acids of the human immunodeficiency virus type I nucleocapsid protein zinc fingers and their involvement in heterologous tRNA(Phe) binding: a steady-state and time-resolved fluorescence study.
Mély Y, Piémont E, Sorinas-Jimeno M, de Rocquigny H, Jullian N, Morellet N, Roques BP, Gérard D. Mély Y, et al. Among authors: morellet n. Biophys J. 1993 Oct;65(4):1513-22. doi: 10.1016/S0006-3495(93)81222-0. Biophys J. 1993. PMID: 8274645 Free PMC article.
89 results