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A new ene-triyne antibiotic from the fungus Baeospora myosura.
Parish CA, Huber J, Baxter J, González A, Collado J, Platas G, Diez MT, Vicente F, Dorso K, Abruzzo G, Wilson K. Parish CA, et al. Among authors: huber j. J Nat Prod. 2004 Nov;67(11):1900-2. doi: 10.1021/np0497853. J Nat Prod. 2004. PMID: 15568786
Synthesis and properties of 2-(naphthosultamyl)methyl-carbapenems with potent anti-MRSA activity: discovery of L-786,392.
Ratcliffe RW, Wilkening RR, Wildonger KJ, Waddell ST, Santorelli GM, Parker DL Jr, Morgan JD, Blizzard TA, Hammond ML, Heck JV, Huber J, Kohler J, Dorso KL, St Rose E, Sundelof JG, May WJ, Hammond GG. Ratcliffe RW, et al. Among authors: huber j. Bioorg Med Chem Lett. 1999 Mar 8;9(5):679-84. doi: 10.1016/s0960-894x(99)00071-2. Bioorg Med Chem Lett. 1999. PMID: 10201828
Chemical genetic identification of peptidoglycan inhibitors potentiating carbapenem activity against methicillin-resistant Staphylococcus aureus.
Huber J, Donald RG, Lee SH, Jarantow LW, Salvatore MJ, Meng X, Painter R, Onishi RH, Occi J, Dorso K, Young K, Park YW, Skwish S, Szymonifka MJ, Waddell TS, Miesel L, Phillips JW, Roemer T. Huber J, et al. Chem Biol. 2009 Aug 28;16(8):837-48. doi: 10.1016/j.chembiol.2009.05.012. Chem Biol. 2009. PMID: 19716474
Reduced immunotoxicity and preservation of antibacterial activity in a releasable side-chain carbapenem antibiotic.
Rosen H, Hajdu R, Silver L, Kropp H, Dorso K, Kohler J, Sundelof JG, Huber J, Hammond GG, Jackson JJ, Gill CJ, Thompson R, Pelak BA, Epstein-Toney JH, Lankas G, Wilkening RR, Wildonger KJ, Blizzard TA, DiNinno FP, Ratcliffe RW, Heck JV, Kozarich JW, Hammond ML. Rosen H, et al. Among authors: huber j. Science. 1999 Jan 29;283(5402):703-6. doi: 10.1126/science.283.5402.703. Science. 1999. PMID: 9924033
2,074 results