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Participation of Smad2, Smad3, and Smad4 in transforming growth factor beta (TGF-beta)-induced activation of Smad7. THE TGF-beta response element of the promoter requires functional Smad binding element and E-box sequences for transcriptional regulation.
Stopa M, Anhuf D, Terstegen L, Gatsios P, Gressner AM, Dooley S. Stopa M, et al. Among authors: dooley s. J Biol Chem. 2000 Sep 22;275(38):29308-17. doi: 10.1074/jbc.M003282200. J Biol Chem. 2000. PMID: 10887185 Free article.
Transforming growth factor beta signal transduction in hepatic stellate cells via Smad2/3 phosphorylation, a pathway that is abrogated during in vitro progression to myofibroblasts. TGFbeta signal transduction during transdifferentiation of hepatic stellate cells.
Dooley S, Delvoux B, Streckert M, Bonzel L, Stopa M, ten Dijke P, Gressner AM. Dooley S, et al. FEBS Lett. 2001 Jul 27;502(1-2):4-10. doi: 10.1016/s0014-5793(01)02656-4. FEBS Lett. 2001. PMID: 11478938 Free article.
Roles of TGF-beta in hepatic fibrosis.
Gressner AM, Weiskirchen R, Breitkopf K, Dooley S. Gressner AM, et al. Among authors: dooley s. Front Biosci. 2002 Apr 1;7:d793-807. doi: 10.2741/A812. Front Biosci. 2002. PMID: 11897555 Review.
489 results