TKK130 is a 3-Hydroxy-Propanamidine (HPA) with Potent Antimalarial In Vivo Activity and a High Barrier to Resistance.
Knaab TC, Moritz A, Pessanha de Carvalho L, Klein S, Lungerich B, Lohse K, Kruse L, Mombo-Ngoma G, Orta L, Thibaud JL, de Villiers KA, Fidock DA, Burckhardt BB, Held J, Wittlin S, Kurz T.
Knaab TC, et al. Among authors: held j.
J Med Chem. 2024 Dec 26. doi: 10.1021/acs.jmedchem.4c01465. Online ahead of print.
J Med Chem. 2024.
PMID: 39723908