Nelson DL - Search Results

1

Design, synthesis and evaluation of bicyclic benzamides as novel 5-HT1F receptor agonists.

Zhang D, Kohlman D, Krushinski J, Liang S, Ying BP, Reilly JE, Dinn SR, Wainscott DB, Nutter S, Gough W, Nelson DL, Schaus JM, Xu YC. Zhang D, et al. Among authors: nelson dl. Bioorg Med Chem Lett. 2004 Dec 20;14(24):6011-6. doi: 10.1016/j.bmcl.2004.09.079. Bioorg Med Chem Lett. 2004. PMID: 15546719

2

Novel potent 5-HT(1F) receptor agonists: structure-activity studies of a series of substituted N-[3-(1-methyl-4-piperidinyl)-1H-pyrrolo[3,2-b]pyridin-5-yl]amides.

Filla SA, Mathes BM, Johnson KW, Phebus LA, Cohen ML, Nelson DL, Zgombick JM, Erickson JA, Schenck KW, Wainscott DB, Branchek TA, Schaus JM. Filla SA, et al. Among authors: nelson dl. J Med Chem. 2003 Jul 3;46(14):3060-71. doi: 10.1021/jm030020m. J Med Chem. 2003. PMID: 12825944

3

Substituted furo[3,2-b]pyridines: novel bioisosteres of 5-HT 1F receptor agonists.

Mathes BM, Hudziak KJ, Schaus JM, Xu YC, Nelson DL, Wainscott DB, Nutter SE, Gough WH, Branchek TA, Zgombick JM, Filla SA. Mathes BM, et al. Among authors: nelson dl. Bioorg Med Chem Lett. 2004 Jan 5;14(1):167-70. doi: 10.1016/j.bmcl.2003.09.091. Bioorg Med Chem Lett. 2004. PMID: 14684321

4

[3H]LY334370, a novel radioligand for the 5-HT1F receptor. I. In vitro characterization of binding properties.

Wainscott DB, Krushinski JH Jr, Audia JE, Schaus JM, Zgombick JM, Lucaites VL, Nelson DL. Wainscott DB, et al. Among authors: nelson dl. Naunyn Schmiedebergs Arch Pharmacol. 2005 Mar;371(3):169-77. doi: 10.1007/s00210-005-1035-9. Epub 2005 Apr 27. Naunyn Schmiedebergs Arch Pharmacol. 2005. PMID: 15900510

5

[3H]LY334370, a novel radioligand for the 5-HT1F receptor. II. Autoradiographic localization in rat, guinea pig, monkey and human brain.

Lucaites VL, Krushinski JH, Schaus JM, Audia JE, Nelson DL. Lucaites VL, et al. Among authors: nelson dl. Naunyn Schmiedebergs Arch Pharmacol. 2005 Mar;371(3):178-84. doi: 10.1007/s00210-005-1036-8. Epub 2005 Apr 27. Naunyn Schmiedebergs Arch Pharmacol. 2005. PMID: 15900511

6

Indoloxypropanolamine analogues as 5-HT(1A) receptor antagonists.

Krushinski JH Jr, Schaus JM, Thompson DC, Calligaro DO, Nelson DL, Luecke SH, Wainscott DB, Wong DT. Krushinski JH Jr, et al. Among authors: nelson dl. Bioorg Med Chem Lett. 2007 Oct 15;17(20):5600-4. doi: 10.1016/j.bmcl.2007.07.086. Epub 2007 Aug 22. Bioorg Med Chem Lett. 2007. PMID: 17804228

7

Discovery of selective N-[3-(1-methyl-piperidine-4-carbonyl)-phenyl]-benzamide-based 5-HT₁ F receptor agonists: Evolution from bicyclic to monocyclic cores.

Zhang D, Blanco MJ, Ying BP, Kohlman D, Liang SX, Victor F, Chen Q, Krushinski J, Filla SA, Hudziak KJ, Mathes BM, Cohen MP, Zacherl D, Nelson DL, Wainscott DB, Nutter SE, Gough WH, Schaus JM, Xu YC. Zhang D, et al. Among authors: nelson dl. Bioorg Med Chem Lett. 2015 Oct 1;25(19):4337-41. doi: 10.1016/j.bmcl.2015.07.042. Epub 2015 Jul 22. Bioorg Med Chem Lett. 2015. PMID: 26271587

8

Advances toward new antidepressants beyond SSRIs: 1-aryloxy-3-piperidinylpropan-2-ols with dual 5-HT1A receptor antagonism/SSRI activities. Part 1.

Takeuchi K, Kohn TJ, Honigschmidt NA, Rocco VP, Spinazze PG, Koch DJ, Nelson DL, Wainscott DB, Ahmad LJ, Shaw J, Threlkeld PG, Wong DT. Takeuchi K, et al. Among authors: nelson dl. Bioorg Med Chem Lett. 2003 Jun 2;13(11):1903-5. doi: 10.1016/s0960-894x(03)00303-2. Bioorg Med Chem Lett. 2003. PMID: 12749894

9

Advances Toward new antidepressants beyond SSRIs: 1-aryloxy-3-piperidinylpropan-2-ols with dual 5-HT(1A) receptor antagonism/SSRI activities. Part 2.

Takeuchi K, Kohn TJ, Honigschmidt NA, Rocco VP, Spinazze PG, Koch DJ, Atkinson ST, Hertel LW, Nelson DL, Wainscott DB, Ahmad LJ, Shaw J, Threlkeld PG, Wong DT. Takeuchi K, et al. Among authors: nelson dl. Bioorg Med Chem Lett. 2003 Jul 21;13(14):2393-7. doi: 10.1016/s0960-894x(03)00392-5. Bioorg Med Chem Lett. 2003. PMID: 12824042

10

Advances toward new antidepressants beyond SSRIs: 1-aryloxy-3-piperidinylpropan-2-ols with dual 5-HT1A receptor antagonism/SSRI activities. Part 3.

Takeuchi K, Kohn TJ, Honigschmidt NA, Rocco VP, Spinazze PG, Atkinson ST, Hertel LW, Nelson DL, Wainscott DB, Ahmad LJ, Shaw J, Threlkeld PG, Wong DT. Takeuchi K, et al. Among authors: nelson dl. Bioorg Med Chem Lett. 2003 Nov 17;13(22):3939-42. doi: 10.1016/j.bmcl.2003.09.002. Bioorg Med Chem Lett. 2003. PMID: 14592479

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