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Page 1
The discovery of VLA-4 antagonists.
Tilley JW, Chen L, Sidduri A, Fotouhi N. Tilley JW, et al. Curr Top Med Chem. 2004;4(14):1509-23. doi: 10.2174/1568026043387502. Curr Top Med Chem. 2004. PMID: 15544541 Review.
N-Cycloalkanoyl-L-phenylalanine derivatives as VCAM/VLA-4 antagonists.
Sidduri A, Tilley JW, Hull K, Lou JP, Kaplan G, Sheffron A, Chen L, Campbell R, Guthrie R, Huang TN, Huby N, Rowan K, Schwinge V, Renzetti LM. Sidduri A, et al. Among authors: tilley jw. Bioorg Med Chem Lett. 2002 Sep 2;12(17):2475-8. doi: 10.1016/s0960-894x(02)00386-4. Bioorg Med Chem Lett. 2002. PMID: 12161161
N-Aroyl-L-phenylalanine derivatives as VCAM/VLA-4 antagonists.
Sidduri A, Tilley JW, Lou JP, Chen L, Kaplan G, Mennona F, Campbell R, Guthrie R, Huang TN, Rowan K, Schwinge V, Renzetti LM. Sidduri A, et al. Among authors: tilley jw. Bioorg Med Chem Lett. 2002 Sep 2;12(17):2479-82. doi: 10.1016/s0960-894x(02)00387-6. Bioorg Med Chem Lett. 2002. PMID: 12161162
Identification of N-acyl 4-(5-pyrimidine-2,4-dionyl)phenylalanine derivatives and their orally active prodrug esters as dual-acting alpha4-beta1 and alpha4-beta7 receptor antagonists.
Sidduri A, Tilley JW, Lou J, Tare N, Cavallo G, Frank K, Pamidimukkala A, Choi DS, Gerber L, Railkar A, Renzetti L. Sidduri A, et al. Among authors: tilley jw. Bioorg Med Chem Lett. 2013 Feb 15;23(4):1026-31. doi: 10.1016/j.bmcl.2012.12.026. Epub 2012 Dec 20. Bioorg Med Chem Lett. 2013. PMID: 23312474
Discovery of novel and potent leukotriene B4 receptor antagonists. Part 1.
Goodnow RA Jr, Hicks A, Sidduri A, Kowalczyk A, Dominique R, Qiao Q, Lou JP, Gillespie P, Fotouhi N, Tilley J, Cohen N, Choudhry S, Cavallo G, Tannu SA, Ventre JD, Lavelle D, Tare NS, Oh H, Lamb M, Kurylko G, Hamid R, Wright MB, Pamidimukkala A, Egan T, Gubler U, Hoffman AF, Wei X, Li YL, O'Neil J, Marcano R, Pozzani K, Molinaro T, Santiago J, Singer L, Hargaden M, Moore D, Catala AR, Chao LC, Hermann G, Venkat R, Mancebo H, Renzetti LM. Goodnow RA Jr, et al. J Med Chem. 2010 May 13;53(9):3502-16. doi: 10.1021/jm1001919. J Med Chem. 2010. PMID: 20380377
Carbacyclic peptide mimetics as VCAM-VLA-4 antagonists.
Tilley J, Kaplan G, Fotouhi N, Wolitzky B, Rowan K. Tilley J, et al. Bioorg Med Chem Lett. 2000 Jun 5;10(11):1163-5. doi: 10.1016/s0960-894x(00)00173-6. Bioorg Med Chem Lett. 2000. PMID: 10866372
N-benzylpyroglutamyl-L-phenylalanine derivatives as VCAM/VLA-4 antagonists.
Chen L, Tilley JW, Guthrie RW, Mennona F, Huang TN, Kaplan G, Trilles R, Miklowski D, Huby N, Schwinge V, Wolitzky B, Rowan K. Chen L, et al. Among authors: tilley jw. Bioorg Med Chem Lett. 2000 Apr 17;10(8):729-33. doi: 10.1016/s0960-894x(00)00089-5. Bioorg Med Chem Lett. 2000. PMID: 10782674
44 results