Wolfenden R - Search Results

1

OMP decarboxylase: an experimental test of electrostatic destabilization of the enzyme-substrate complex.

Callahan BP, Wolfenden R. Callahan BP, et al. Among authors: wolfenden r. J Am Chem Soc. 2004 Nov 17;126(45):14698-9. doi: 10.1021/ja0450049. J Am Chem Soc. 2004. PMID: 15535676

2

Orotidine-5'-monophosphate decarboxylase catalysis: kinetic isotope effects and the state of hybridization of a bound transition-state analogue.

Acheson SA, Bell JB, Jones ME, Wolfenden R. Acheson SA, et al. Among authors: wolfenden r. Biochemistry. 1990 Apr 3;29(13):3198-202. doi: 10.1021/bi00465a007. Biochemistry. 1990. PMID: 2334689

3

A proficient enzyme.

Radzicka A, Wolfenden R. Radzicka A, et al. Among authors: wolfenden r. Science. 1995 Jan 6;267(5194):90-3. doi: 10.1126/science.7809611. Science. 1995. PMID: 7809611

4

Activity of yeast orotidine-5'-phosphate decarboxylase in the absence of metals.

Miller BG, Smiley JA, Short SA, Wolfenden R. Miller BG, et al. Among authors: wolfenden r. J Biol Chem. 1999 Aug 20;274(34):23841-3. doi: 10.1074/jbc.274.34.23841. J Biol Chem. 1999. PMID: 10446147 Free article.

5

Anatomy of a proficient enzyme: the structure of orotidine 5'-monophosphate decarboxylase in the presence and absence of a potential transition state analog.

Miller BG, Hassell AM, Wolfenden R, Milburn MV, Short SA. Miller BG, et al. Among authors: wolfenden r. Proc Natl Acad Sci U S A. 2000 Feb 29;97(5):2011-6. doi: 10.1073/pnas.030409797. Proc Natl Acad Sci U S A. 2000. PMID: 10681417 Free PMC article.

6

Contribution of enzyme-phosphoribosyl contacts to catalysis by orotidine 5'-phosphate decarboxylase.

Miller BG, Snider MJ, Short SA, Wolfenden R. Miller BG, et al. Among authors: wolfenden r. Biochemistry. 2000 Jul 18;39(28):8113-8. doi: 10.1021/bi000818x. Biochemistry. 2000. PMID: 10889016

7

Dissecting a charged network at the active site of orotidine-5'-phosphate decarboxylase.

Miller BG, Snider MJ, Wolfenden R, Short SA. Miller BG, et al. Among authors: wolfenden r. J Biol Chem. 2001 May 4;276(18):15174-6. doi: 10.1074/jbc.M011429200. Epub 2001 Jan 30. J Biol Chem. 2001. PMID: 11278904 Free article.

8

Role of enzyme-ribofuranosyl contacts in the ground state and transition state for orotidine 5'-phosphate decarboxylase: a role for substrate destabilization?

Miller BG, Butterfoss GL, Short SA, Wolfenden R. Miller BG, et al. Among authors: wolfenden r. Biochemistry. 2001 May 29;40(21):6227-32. doi: 10.1021/bi0028993. Biochemistry. 2001. PMID: 11371183

9

Equilibrium of formation of the 6-carbanion of UMP, a potential intermediate in the action of OMP decarboxylase.

Sievers A, Wolfenden R. Sievers A, et al. Among authors: wolfenden r. J Am Chem Soc. 2002 Nov 27;124(47):13986-7. doi: 10.1021/ja021073g. J Am Chem Soc. 2002. PMID: 12440884

10

Migration of methyl groups between aliphatic amines in water.

Callahan BP, Wolfenden R. Callahan BP, et al. Among authors: wolfenden r. J Am Chem Soc. 2003 Jan 15;125(2):310-1. doi: 10.1021/ja021212u. J Am Chem Soc. 2003. PMID: 12517124

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