Timmers HT - Search Results

1

Solution structure of the ubiquitin-conjugating enzyme UbcH5B.

Houben K, Dominguez C, van Schaik FM, Timmers HT, Bonvin AM, Boelens R. Houben K, et al. Among authors: timmers ht. J Mol Biol. 2004 Nov 19;344(2):513-26. doi: 10.1016/j.jmb.2004.09.054. J Mol Biol. 2004. PMID: 15522302

2

An altered-specificity ubiquitin-conjugating enzyme/ubiquitin-protein ligase pair.

Winkler GS, Albert TK, Dominguez C, Legtenberg YI, Boelens R, Timmers HT. Winkler GS, et al. Among authors: timmers ht. J Mol Biol. 2004 Mar 12;337(1):157-65. doi: 10.1016/j.jmb.2004.01.031. J Mol Biol. 2004. PMID: 15001359

3

Structural model of the UbcH5B/CNOT4 complex revealed by combining NMR, mutagenesis, and docking approaches.

Dominguez C, Bonvin AM, Winkler GS, van Schaik FM, Timmers HT, Boelens R. Dominguez C, et al. Among authors: timmers ht. Structure. 2004 Apr;12(4):633-44. doi: 10.1016/j.str.2004.03.004. Structure. 2004. PMID: 15062086 Free article.

4

Dynamics and metal exchange properties of C4C4 RING domains from CNOT4 and the p44 subunit of TFIIH.

Houben K, Wasielewski E, Dominguez C, Kellenberger E, Atkinson RA, Timmers HT, Kieffer B, Boelens R. Houben K, et al. Among authors: timmers ht. J Mol Biol. 2005 Jun 10;349(3):621-37. doi: 10.1016/j.jmb.2005.04.007. Epub 2005 Apr 21. J Mol Biol. 2005. PMID: 15890366

5

E2-c-Cbl recognition is necessary but not sufficient for ubiquitination activity.

Huang A, de Jong RN, Wienk H, Winkler GS, Timmers HT, Boelens R. Huang A, et al. Among authors: timmers ht. J Mol Biol. 2009 Jan 16;385(2):507-19. doi: 10.1016/j.jmb.2008.10.044. Epub 2008 Nov 1. J Mol Biol. 2009. PMID: 18996392

6

A comprehensive framework of E2-RING E3 interactions of the human ubiquitin-proteasome system.

van Wijk SJ, de Vries SJ, Kemmeren P, Huang A, Boelens R, Bonvin AM, Timmers HT. van Wijk SJ, et al. Among authors: timmers ht. Mol Syst Biol. 2009;5:295. doi: 10.1038/msb.2009.55. Epub 2009 Aug 18. Mol Syst Biol. 2009. PMID: 19690564 Free PMC article.

7

Identification of a ubiquitin-protein ligase subunit within the CCR4-NOT transcription repressor complex.

Albert TK, Hanzawa H, Legtenberg YI, de Ruwe MJ, van den Heuvel FA, Collart MA, Boelens R, Timmers HT. Albert TK, et al. Among authors: timmers ht. EMBO J. 2002 Feb 1;21(3):355-64. doi: 10.1093/emboj/21.3.355. EMBO J. 2002. PMID: 11823428 Free PMC article.

8

Structural insight into the recognition of the H3K4me3 mark by the TFIID subunit TAF3.

van Ingen H, van Schaik FM, Wienk H, Ballering J, Rehmann H, Dechesne AC, Kruijzer JA, Liskamp RM, Timmers HT, Boelens R. van Ingen H, et al. Among authors: timmers ht. Structure. 2008 Aug 6;16(8):1245-56. doi: 10.1016/j.str.2008.04.015. Structure. 2008. PMID: 18682226 Free article.

9

Dynamic control of selectivity in the ubiquitination pathway revealed by an ASP to GLU substitution in an intra-molecular salt-bridge network.

van Wijk SJ, Melquiond AS, de Vries SJ, Timmers HT, Bonvin AM. van Wijk SJ, et al. Among authors: timmers ht. PLoS Comput Biol. 2012;8(11):e1002754. doi: 10.1371/journal.pcbi.1002754. Epub 2012 Nov 1. PLoS Comput Biol. 2012. PMID: 23133359 Free PMC article.

10

The structure of the C4C4 ring finger of human NOT4 reveals features distinct from those of C3HC4 RING fingers.

Hanzawa H, de Ruwe MJ, Albert TK, van Der Vliet PC, Timmers HT, Boelens R. Hanzawa H, et al. Among authors: timmers ht. J Biol Chem. 2001 Mar 30;276(13):10185-90. doi: 10.1074/jbc.M009298200. Epub 2000 Nov 21. J Biol Chem. 2001. PMID: 11087754 Free article.

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