Hargreaves I - Search Results

1

Neuroprotective role of the Reaper-related serine protease HtrA2/Omi revealed by targeted deletion in mice.

Martins LM, Morrison A, Klupsch K, Fedele V, Moisoi N, Teismann P, Abuin A, Grau E, Geppert M, Livi GP, Creasy CL, Martin A, Hargreaves I, Heales SJ, Okada H, Brandner S, Schulz JB, Mak T, Downward J. Martins LM, et al. Among authors: hargreaves i. Mol Cell Biol. 2004 Nov;24(22):9848-62. doi: 10.1128/MCB.24.22.9848-9862.2004. Mol Cell Biol. 2004. PMID: 15509788 Free PMC article.

2

PINK1 is necessary for long term survival and mitochondrial function in human dopaminergic neurons.

Wood-Kaczmar A, Gandhi S, Yao Z, Abramov AY, Miljan EA, Keen G, Stanyer L, Hargreaves I, Klupsch K, Deas E, Downward J, Mansfield L, Jat P, Taylor J, Heales S, Duchen MR, Latchman D, Tabrizi SJ, Wood NW. Wood-Kaczmar A, et al. Among authors: hargreaves i. PLoS One. 2008 Jun 18;3(6):e2455. doi: 10.1371/journal.pone.0002455. PLoS One. 2008. PMID: 18560593 Free PMC article.

3

Neonatal presentation of coenzyme Q10 deficiency.

Rahman S, Hargreaves I, Clayton P, Heales S. Rahman S, et al. Among authors: hargreaves i. J Pediatr. 2001 Sep;139(3):456-8. doi: 10.1067/mpd.2001.117575. J Pediatr. 2001. PMID: 11562630

4

Mitochondrial respiratory chain defects are not accompanied by an increase in the activities of lactate dehydrogenase or manganese superoxide dismutase in paediatric skeletal muscle biopsies.

Hargreaves IP, Heales SJ, Land JM. Hargreaves IP, et al. J Inherit Metab Dis. 1999 Dec;22(8):925-31. doi: 10.1023/a:1005643508075. J Inherit Metab Dis. 1999. PMID: 10604144

5

Mitochondrial disease: a historical, biochemical, and London perspective.

Land JM, Morgan-Hughes JA, Hargreaves I, Heales SJ. Land JM, et al. Among authors: hargreaves i. Neurochem Res. 2004 Mar;29(3):483-91. doi: 10.1023/b:nere.0000014819.53972.b0. Neurochem Res. 2004. PMID: 15038596 Review.

6

Phenotypic variability of mitochondrial disease caused by a nuclear mutation in complex II.

Pagnamenta AT, Hargreaves IP, Duncan AJ, Taanman JW, Heales SJ, Land JM, Bitner-Glindzicz M, Leonard JV, Rahman S. Pagnamenta AT, et al. Mol Genet Metab. 2006 Nov;89(3):214-21. doi: 10.1016/j.ymgme.2006.05.003. Epub 2006 Jun 23. Mol Genet Metab. 2006. PMID: 16798039

7

Assessment of Mitochondrial Dysfunction in Experimental Autoimmune Encephalomyelitis (EAE) Models of Multiple Sclerosis.

Ng X, Sadeghian M, Heales S, Hargreaves IP. Ng X, et al. Int J Mol Sci. 2019 Oct 9;20(20):4975. doi: 10.3390/ijms20204975. Int J Mol Sci. 2019. PMID: 31600882 Free PMC article.

8

Determination of coenzyme Q10 status in blood mononuclear cells, skeletal muscle, and plasma by HPLC with di-propoxy-coenzyme Q10 as an internal standard.

Duncan AJ, Heales SJ, Mills K, Eaton S, Land JM, Hargreaves IP. Duncan AJ, et al. Clin Chem. 2005 Dec;51(12):2380-2. doi: 10.1373/clinchem.2005.054643. Clin Chem. 2005. PMID: 16306103 No abstract available.

9

Some observations upon biochemical causes of ataxia and a new disease entity ubiquinone, CoQ10 deficiency.

Land JM, Heales SJ, Duncan AJ, Hargreaves IP. Land JM, et al. Neurochem Res. 2007 Apr-May;32(4-5):837-43. doi: 10.1007/s11064-006-9222-8. Epub 2006 Dec 21. Neurochem Res. 2007. PMID: 17186372 Review.

10

Human neuronal coenzyme Q10 deficiency results in global loss of mitochondrial respiratory chain activity, increased mitochondrial oxidative stress and reversal of ATP synthase activity: implications for pathogenesis and treatment.

Duberley KE, Abramov AY, Chalasani A, Heales SJ, Rahman S, Hargreaves IP. Duberley KE, et al. J Inherit Metab Dis. 2013 Jan;36(1):63-73. doi: 10.1007/s10545-012-9511-0. Epub 2012 Jul 6. J Inherit Metab Dis. 2013. PMID: 22767283

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