Ishikawa T - Search Results

1

Functional evaluation of ABCB1 (P-glycoprotein) polymorphisms: high-speed screening and structure-activity relationship analyses.

Ishikawa T, Hirano H, Onishi Y, Sakurai A, Tarui S. Ishikawa T, et al. Drug Metab Pharmacokinet. 2004 Feb;19(1):1-14. doi: 10.2133/dmpk.19.1. Drug Metab Pharmacokinet. 2004. PMID: 15499164 Free article. Review.

2

Pharmacogenomics of drug transporters: a new approach to functional analysis of the genetic polymorphisms of ABCB1 (P-glycoprotein/MDR1).

Ishikawa T, Onishi Y, Hirano H, Oosumi K, Nagakura M, Tarui S. Ishikawa T, et al. Biol Pharm Bull. 2004 Jul;27(7):939-48. doi: 10.1248/bpb.27.939. Biol Pharm Bull. 2004. PMID: 15256718 Free article. Review.

3

Does ABCG2 need a heterodimer partner? Expression and functional evaluation of ABCG2 (Arg 482)*.

Yoshikawa M, Kasamatsu S, Yasunaga M, Wang G, Ikegami Y, Yoshida H, Tarui S, Yabuuchi H, Ishikawa T. Yoshikawa M, et al. Among authors: ishikawa t. Drug Metab Pharmacokinet. 2002;17(2):130-5. doi: 10.2133/dmpk.17.130. Drug Metab Pharmacokinet. 2002. PMID: 15618661 Free article.

4

Genetic polymorphisms of ATP-binding cassette transporters ABCB1 and ABCG2: therapeutic implications.

Sakurai A, Tamura A, Onishi Y, Ishikawa T. Sakurai A, et al. Among authors: ishikawa t. Expert Opin Pharmacother. 2005 Nov;6(14):2455-73. doi: 10.1517/14656566.6.14.2455. Expert Opin Pharmacother. 2005. PMID: 16259577 Review.

5

High-speed screening of human ATP-binding cassette transporter function and genetic polymorphisms: new strategies in pharmacogenomics.

Ishikawa T, Sakurai A, Kanamori Y, Nagakura M, Hirano H, Takarada Y, Yamada K, Fukushima K, Kitajima M. Ishikawa T, et al. Methods Enzymol. 2005;400:485-510. doi: 10.1016/S0076-6879(05)00027-3. Methods Enzymol. 2005. PMID: 16399366

6

A new strategy of high-speed screening and quantitative structure-activity relationship analysis to evaluate human ATP-binding cassette transporter ABCG2-drug interactions.

Saito H, Hirano H, Nakagawa H, Fukami T, Oosumi K, Murakami K, Kimura H, Kouchi T, Konomi M, Tao E, Tsujikawa N, Tarui S, Nagakura M, Osumi M, Ishikawa T. Saito H, et al. Among authors: ishikawa t. J Pharmacol Exp Ther. 2006 Jun;317(3):1114-24. doi: 10.1124/jpet.105.099036. Epub 2006 Feb 17. J Pharmacol Exp Ther. 2006. PMID: 16489126

7

High-speed screening and QSAR analysis of human ATP-binding cassette transporter ABCB11 (bile salt export pump) to predict drug-induced intrahepatic cholestasis.

Hirano H, Kurata A, Onishi Y, Sakurai A, Saito H, Nakagawa H, Nagakura M, Tarui S, Kanamori Y, Kitajima M, Ishikawa T. Hirano H, et al. Among authors: ishikawa t. Mol Pharm. 2006 May-Jun;3(3):252-65. doi: 10.1021/mp060004w. Mol Pharm. 2006. PMID: 16749857

8

Human ABC transporter ABCG2 in xenobiotic protection and redox biology.

Wakabayashi K, Tamura A, Saito H, Onishi Y, Ishikawa T. Wakabayashi K, et al. Among authors: ishikawa t. Drug Metab Rev. 2006;38(3):371-91. doi: 10.1080/03602530600727947. Drug Metab Rev. 2006. PMID: 16877258 Review.

9

Evaluation of human P-glycoprotein (MDR1/ABCB1) ATPase activity assay method by comparing with in vitro transport measurements: Michaelis-Menten kinetic analysis to estimate the affinity of P-glycoprotein to drugs.

Shirasaka Y, Onishi Y, Sakurai A, Nakagawa H, Ishikawa T, Yamashita S. Shirasaka Y, et al. Among authors: ishikawa t. Biol Pharm Bull. 2006 Dec;29(12):2465-71. doi: 10.1248/bpb.29.2465. Biol Pharm Bull. 2006. PMID: 17142983 Free article.

10

Prediction of drug-induced intrahepatic cholestasis: in vitro screening and QSAR analysis of drugs inhibiting the human bile salt export pump.

Sakurai A, Kurata A, Onishi Y, Hirano H, Ishikawa T. Sakurai A, et al. Among authors: ishikawa t. Expert Opin Drug Saf. 2007 Jan;6(1):71-86. doi: 10.1517/14740338.6.1.71. Expert Opin Drug Saf. 2007. PMID: 17181454 Review.

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