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Lowering of Pkd1 expression is sufficient to cause polycystic kidney disease.
Lantinga-van Leeuwen IS, Dauwerse JG, Baelde HJ, Leonhard WN, van de Wal A, Ward CJ, Verbeek S, Deruiter MC, Breuning MH, de Heer E, Peters DJ. Lantinga-van Leeuwen IS, et al. Among authors: deruiter mc. Hum Mol Genet. 2004 Dec 15;13(24):3069-77. doi: 10.1093/hmg/ddh336. Epub 2004 Oct 20. Hum Mol Genet. 2004. PMID: 15496422
Pkd1-inactivation in vascular smooth muscle cells and adaptation to hypertension.
Hassane S, Claij N, Jodar M, Dedman A, Lauritzen I, Duprat F, Koenderman JS, van der Wal A, Breuning MH, de Heer E, Honore E, DeRuiter MC, Peters DJ. Hassane S, et al. Among authors: deruiter mc. Lab Invest. 2011 Jan;91(1):24-32. doi: 10.1038/labinvest.2010.159. Epub 2010 Sep 20. Lab Invest. 2011. PMID: 20856231 Free article.
Intrauterine exposure to maternal atherosclerotic risk factors increases the susceptibility to atherosclerosis in adult life.
Alkemade FE, Gittenberger-de Groot AC, Schiel AE, VanMunsteren JC, Hogers B, van Vliet LS, Poelmann RE, Havekes LM, Willems van Dijk K, DeRuiter MC. Alkemade FE, et al. Among authors: deruiter mc. Arterioscler Thromb Vasc Biol. 2007 Oct;27(10):2228-35. doi: 10.1161/01.ATV.0000282193.31936.fd. Epub 2007 Jul 26. Arterioscler Thromb Vasc Biol. 2007. PMID: 17656671
Prenatal exposure to apoE deficiency and postnatal hypercholesterolemia are associated with altered cell-specific lysine methyltransferase and histone methylation patterns in the vasculature.
Alkemade FE, van Vliet P, Henneman P, van Dijk KW, Hierck BP, van Munsteren JC, Scheerman JA, Goeman JJ, Havekes LM, Gittenberger-de Groot AC, van den Elsen PJ, DeRuiter MC. Alkemade FE, et al. Among authors: deruiter mc. Am J Pathol. 2010 Feb;176(2):542-8. doi: 10.2353/ajpath.2010.090031. Epub 2009 Dec 24. Am J Pathol. 2010. PMID: 20035052 Free PMC article.
183 results