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The role of biopharmaceutics in the development of a clinical nanoparticle formulation of MK-0869: a Beagle dog model predicts improved bioavailability and diminished food effect on absorption in human.
Wu Y, Loper A, Landis E, Hettrick L, Novak L, Lynn K, Chen C, Thompson K, Higgins R, Batra U, Shelukar S, Kwei G, Storey D. Wu Y, et al. Among authors: loper a. Int J Pharm. 2004 Nov 5;285(1-2):135-46. doi: 10.1016/j.ijpharm.2004.08.001. Int J Pharm. 2004. PMID: 15488686
Identification of oxidative degradates of the thrombin inhibitor, 3-(2-phenethylamino)-6-methyl-1-(2-amino-6-methyl-5-methyleneca rboxamidomethylpyridinyl)pyrazinone, using liquid chromatography/mass spectrometry and liquid chromatography/tandem mass spectrometry.
Wu Y, Chen X, Gier L, Almarsson O, Ostovic D, Loper AE. Wu Y, et al. Among authors: loper ae. J Pharm Biomed Anal. 1999 Jul;20(3):471-85. doi: 10.1016/s0731-7085(99)00035-7. J Pharm Biomed Anal. 1999. PMID: 10701963
37 results