Shih C - Search Results

1

Acyl sulfonamide anti-proliferatives: benzene substituent structure-activity relationships for a novel class of antitumor agents.

Lobb KL, Hipskind PA, Aikins JA, Alvarez E, Cheung YY, Considine EL, De Dios A, Durst GL, Ferritto R, Grossman CS, Giera DD, Hollister BA, Huang Z, Iversen PW, Law KL, Li T, Lin HS, Lopez B, Lopez JE, Cabrejas LM, McCann DJ, Molero V, Reilly JE, Richett ME, Shih C, Teicher B, Wikel JH, White WT, Mader MM. Lobb KL, et al. Among authors: shih c. J Med Chem. 2004 Oct 21;47(22):5367-80. doi: 10.1021/jm030594r. J Med Chem. 2004. PMID: 15481975

2

Synthesis, structure-activity relationship, and biological studies of indolocarbazoles as potent cyclin D1-CDK4 inhibitors.

Zhu G, Conner SE, Zhou X, Shih C, Li T, Anderson BD, Brooks HB, Campbell RM, Considine E, Dempsey JA, Faul MM, Ogg C, Patel B, Schultz RM, Spencer CD, Teicher B, Watkins SA. Zhu G, et al. Among authors: shih c. J Med Chem. 2003 May 22;46(11):2027-30. doi: 10.1021/jm0256169. J Med Chem. 2003. PMID: 12747775

3

Acyl sulfonamide anti-proliferatives. Part 2: activity of heterocyclic sulfonamide derivatives.

Mader MM, Shih C, Considine E, Dios AD, Grossman CS, Hipskind PA, Lin HS, Lobb KL, Lopez B, Lopez JE, Cabrejas LM, Richett ME, White WT, Cheung YY, Huang Z, Reilly JE, Dinn SR. Mader MM, et al. Among authors: shih c. Bioorg Med Chem Lett. 2005 Feb 1;15(3):617-20. doi: 10.1016/j.bmcl.2004.11.041. Bioorg Med Chem Lett. 2005. PMID: 15664824

4

Antiangiogenic effects of a protein kinase Cbeta-selective small molecule.

Teicher BA, Alvarez E, Menon K, Esterman MA, Considine E, Shih C, Faul MM. Teicher BA, et al. Among authors: shih c. Cancer Chemother Pharmacol. 2002 Jan;49(1):69-77. doi: 10.1007/s00280-001-0386-2. Cancer Chemother Pharmacol. 2002. PMID: 11855754

5

Antiangiogenic and antitumor effects of a protein kinase Cbeta inhibitor in human breast cancer and ovarian cancer xenografts.

Teicher BA, Menon K, Alvarez E, Shih C, Faul MM. Teicher BA, et al. Among authors: shih c. Invest New Drugs. 2002 Aug;20(3):241-51. doi: 10.1023/a:1016297611825. Invest New Drugs. 2002. PMID: 12201487

6

Synthesis of quinolinyl/isoquinolinyl[a]pyrrolo [3,4-c] carbazoles as cyclin D1/CDK4 inhibitors.

Zhu G, Conner S, Zhou X, Shih C, Brooks HB, Considine E, Dempsey JA, Ogg C, Patel B, Schultz RM, Spencer CD, Teicher B, Watkins SA. Zhu G, et al. Among authors: shih c. Bioorg Med Chem Lett. 2003 Apr 7;13(7):1231-5. doi: 10.1016/s0960-894x(03)00133-1. Bioorg Med Chem Lett. 2003. PMID: 12657252

7

Novel, potent and selective cyclin D1/CDK4 inhibitors: indolo[6,7-a]pyrrolo[3,4-c]carbazoles.

Engler TA, Furness K, Malhotra S, Sanchez-Martinez C, Shih C, Xie W, Zhu G, Zhou X, Conner S, Faul MM, Sullivan KA, Kolis SP, Brooks HB, Patel B, Schultz RM, DeHahn TB, Kirmani K, Spencer CD, Watkins SA, Considine EL, Dempsey JA, Ogg CA, Stamm NB, Anderson BD, Campbell RM, Vasudevan V, Lytle ML. Engler TA, et al. Among authors: shih c. Bioorg Med Chem Lett. 2003 Jul 21;13(14):2261-7. doi: 10.1016/s0960-894x(03)00461-x. Bioorg Med Chem Lett. 2003. PMID: 12824014

8

Synthesis of 1,7-annulated indoles and their applications in the studies of cyclin dependent kinase inhibitors.

Zhu G, Conner SE, Zhou X, Chan HK, Shih C, Engler TA, Al-Awar RS, Brooks HB, Watkins SA, Spencer CD, Schultz RM, Dempsey JA, Considine EL, Patel BR, Ogg CA, Vasudevan V, Lytle ML. Zhu G, et al. Among authors: shih c. Bioorg Med Chem Lett. 2004 Jun 21;14(12):3057-61. doi: 10.1016/j.bmcl.2004.04.033. Bioorg Med Chem Lett. 2004. PMID: 15149644

9

Preparation of novel aza-1,7-annulated indoles and their conversion to potent indolocarbazole kinase inhibitors.

Al-awar RS, Ray JE, Hecker KA, Joseph S, Huang J, Shih C, Brooks HB, Spencer CD, Watkins SA, Schultz RM, Considine EL, Faul MM, Sullivan KA, Kolis SP, Carr MA, Zhang F. Al-awar RS, et al. Among authors: shih c. Bioorg Med Chem Lett. 2004 Aug 2;14(15):3925-8. doi: 10.1016/j.bmcl.2004.05.088. Bioorg Med Chem Lett. 2004. PMID: 15225699

10

Design of potent and selective 2-aminobenzimidazole-based p38alpha MAP kinase inhibitors with excellent in vivo efficacy.

de Dios A, Shih C, López de Uralde B, Sánchez C, del Prado M, Martín Cabrejas LM, Pleite S, Blanco-Urgoiti J, Lorite MJ, Nevill CR Jr, Bonjouklian R, York J, Vieth M, Wang Y, Magnus N, Campbell RM, Anderson BD, McCann DJ, Giera DD, Lee PA, Schultz RM, Li LC, Johnson LM, Wolos JA. de Dios A, et al. Among authors: shih c. J Med Chem. 2005 Apr 7;48(7):2270-3. doi: 10.1021/jm048978k. J Med Chem. 2005. PMID: 15801819

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