Considine EL - Search Results

1

Acyl sulfonamide anti-proliferatives: benzene substituent structure-activity relationships for a novel class of antitumor agents.

Lobb KL, Hipskind PA, Aikins JA, Alvarez E, Cheung YY, Considine EL, De Dios A, Durst GL, Ferritto R, Grossman CS, Giera DD, Hollister BA, Huang Z, Iversen PW, Law KL, Li T, Lin HS, Lopez B, Lopez JE, Cabrejas LM, McCann DJ, Molero V, Reilly JE, Richett ME, Shih C, Teicher B, Wikel JH, White WT, Mader MM. Lobb KL, et al. Among authors: considine el. J Med Chem. 2004 Oct 21;47(22):5367-80. doi: 10.1021/jm030594r. J Med Chem. 2004. PMID: 15481975

2

Synthesis, structure-activity relationship, and biological studies of indolocarbazoles as potent cyclin D1-CDK4 inhibitors.

Zhu G, Conner SE, Zhou X, Shih C, Li T, Anderson BD, Brooks HB, Campbell RM, Considine E, Dempsey JA, Faul MM, Ogg C, Patel B, Schultz RM, Spencer CD, Teicher B, Watkins SA. Zhu G, et al. J Med Chem. 2003 May 22;46(11):2027-30. doi: 10.1021/jm0256169. J Med Chem. 2003. PMID: 12747775

3

Acyl sulfonamide anti-proliferatives. Part 2: activity of heterocyclic sulfonamide derivatives.

Mader MM, Shih C, Considine E, Dios AD, Grossman CS, Hipskind PA, Lin HS, Lobb KL, Lopez B, Lopez JE, Cabrejas LM, Richett ME, White WT, Cheung YY, Huang Z, Reilly JE, Dinn SR. Mader MM, et al. Bioorg Med Chem Lett. 2005 Feb 1;15(3):617-20. doi: 10.1016/j.bmcl.2004.11.041. Bioorg Med Chem Lett. 2005. PMID: 15664824

4

Antiangiogenic effects of a protein kinase Cbeta-selective small molecule.

Teicher BA, Alvarez E, Menon K, Esterman MA, Considine E, Shih C, Faul MM. Teicher BA, et al. Cancer Chemother Pharmacol. 2002 Jan;49(1):69-77. doi: 10.1007/s00280-001-0386-2. Cancer Chemother Pharmacol. 2002. PMID: 11855754

5

Synthesis of quinolinyl/isoquinolinyl[a]pyrrolo [3,4-c] carbazoles as cyclin D1/CDK4 inhibitors.

Zhu G, Conner S, Zhou X, Shih C, Brooks HB, Considine E, Dempsey JA, Ogg C, Patel B, Schultz RM, Spencer CD, Teicher B, Watkins SA. Zhu G, et al. Bioorg Med Chem Lett. 2003 Apr 7;13(7):1231-5. doi: 10.1016/s0960-894x(03)00133-1. Bioorg Med Chem Lett. 2003. PMID: 12657252

6

Preparation of novel aza-1,7-annulated indoles and their conversion to potent indolocarbazole kinase inhibitors.

Al-awar RS, Ray JE, Hecker KA, Joseph S, Huang J, Shih C, Brooks HB, Spencer CD, Watkins SA, Schultz RM, Considine EL, Faul MM, Sullivan KA, Kolis SP, Carr MA, Zhang F. Al-awar RS, et al. Among authors: considine el. Bioorg Med Chem Lett. 2004 Aug 2;14(15):3925-8. doi: 10.1016/j.bmcl.2004.05.088. Bioorg Med Chem Lett. 2004. PMID: 15225699

7

Novel, potent and selective cyclin D1/CDK4 inhibitors: indolo[6,7-a]pyrrolo[3,4-c]carbazoles.

Engler TA, Furness K, Malhotra S, Sanchez-Martinez C, Shih C, Xie W, Zhu G, Zhou X, Conner S, Faul MM, Sullivan KA, Kolis SP, Brooks HB, Patel B, Schultz RM, DeHahn TB, Kirmani K, Spencer CD, Watkins SA, Considine EL, Dempsey JA, Ogg CA, Stamm NB, Anderson BD, Campbell RM, Vasudevan V, Lytle ML. Engler TA, et al. Among authors: considine el. Bioorg Med Chem Lett. 2003 Jul 21;13(14):2261-7. doi: 10.1016/s0960-894x(03)00461-x. Bioorg Med Chem Lett. 2003. PMID: 12824014

8

Synthesis of 1,7-annulated indoles and their applications in the studies of cyclin dependent kinase inhibitors.

Zhu G, Conner SE, Zhou X, Chan HK, Shih C, Engler TA, Al-Awar RS, Brooks HB, Watkins SA, Spencer CD, Schultz RM, Dempsey JA, Considine EL, Patel BR, Ogg CA, Vasudevan V, Lytle ML. Zhu G, et al. Among authors: considine el. Bioorg Med Chem Lett. 2004 Jun 21;14(12):3057-61. doi: 10.1016/j.bmcl.2004.04.033. Bioorg Med Chem Lett. 2004. PMID: 15149644

9

Properties of bisphosphonates in the 13762 rat mammary carcinoma model of tumor-induced bone resorption.

Alvarez E, Westmore M, Galvin RJ, Clapp CL, Considine EL, Smith SJ, Keyes K, Iversen PW, Delafuente DM, Sulaimon S, Zambrano C, Ma L, Sato M, Martin TJ, Teicher BA, Galbreath EJ. Alvarez E, et al. Among authors: considine el. Clin Cancer Res. 2003 Nov 15;9(15):5705-13. Clin Cancer Res. 2003. PMID: 14654555

10

Studies on cyclin-dependent kinase inhibitors: indolo-[2,3-a]pyrrolo[3,4-c]carbazoles versus bis-indolylmaleimides.

Sanchez-Martinez C, Shih C, Zhu G, Li T, Brooks HB, Patel BK, Schultz RM, DeHahn TB, Spencer CD, Watkins SA, Ogg CA, Considine E, Dempsey JA, Zhang F. Sanchez-Martinez C, et al. Bioorg Med Chem Lett. 2003 Nov 3;13(21):3841-6. doi: 10.1016/s0960-894x(03)00792-3. Bioorg Med Chem Lett. 2003. PMID: 14552792

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