Reddy SA - Search Results

1

The PI 3-kinase/Akt signaling pathway is activated due to aberrant Pten expression and targets transcription factors NF-kappaB and c-Myc in pancreatic cancer cells.

Asano T, Yao Y, Zhu J, Li D, Abbruzzese JL, Reddy SA. Asano T, et al. Among authors: reddy sa. Oncogene. 2004 Nov 11;23(53):8571-80. doi: 10.1038/sj.onc.1207902. Oncogene. 2004. PMID: 15467756

2

Hdm2 is regulated by K-Ras and mediates p53-independent functions in pancreatic cancer cells.

Sui X, Shin S, Zhang R, Firozi PF, Yang L, Abbruzzese JL, Reddy SA. Sui X, et al. Among authors: reddy sa. Oncogene. 2009 Feb 5;28(5):709-20. doi: 10.1038/onc.2008.423. Epub 2008 Nov 24. Oncogene. 2009. PMID: 19029954

3

The rapamycin analog CCI-779 is a potent inhibitor of pancreatic cancer cell proliferation.

Asano T, Yao Y, Zhu J, Li D, Abbruzzese JL, Reddy SA. Asano T, et al. Among authors: reddy sa. Biochem Biophys Res Commun. 2005 May 27;331(1):295-302. doi: 10.1016/j.bbrc.2005.03.166. Biochem Biophys Res Commun. 2005. PMID: 15845392

4

Insulin receptor substrate is a mediator of phosphoinositide 3-kinase activation in quiescent pancreatic cancer cells.

Asano T, Yao Y, Shin S, McCubrey J, Abbruzzese JL, Reddy SA. Asano T, et al. Among authors: reddy sa. Cancer Res. 2005 Oct 15;65(20):9164-8. doi: 10.1158/0008-5472.CAN-05-0779. Cancer Res. 2005. PMID: 16230374

5

Establishment of three-dimensional cultures of human pancreatic duct epithelial cells.

Gutierrez-Barrera AM, Menter DG, Abbruzzese JL, Reddy SA. Gutierrez-Barrera AM, et al. Among authors: reddy sa. Biochem Biophys Res Commun. 2007 Jul 6;358(3):698-703. doi: 10.1016/j.bbrc.2007.04.166. Epub 2007 May 4. Biochem Biophys Res Commun. 2007. PMID: 17512909 Free PMC article.

6

Activator protein-1 has an essential role in pancreatic cancer cells and is regulated by a novel Akt-mediated mechanism.

Shin S, Asano T, Yao Y, Zhang R, Claret FX, Korc M, Sabapathy K, Menter DG, Abbruzzese JL, Reddy SAG. Shin S, et al. Mol Cancer Res. 2009 May;7(5):745-754. doi: 10.1158/1541-7786.MCR-08-0462. Epub 2009 May 12. Mol Cancer Res. 2009. PMID: 19435822 Free PMC article.

7

Tumor suppressor MMAC/PTEN inhibits cytokine-induced NFkappaB activation without interfering with the IkappaB degradation pathway.

Koul D, Yao Y, Abbruzzese JL, Yung WK, Reddy SA. Koul D, et al. Among authors: reddy sa. J Biol Chem. 2001 Apr 6;276(14):11402-8. doi: 10.1074/jbc.M007806200. Epub 2001 Jan 12. J Biol Chem. 2001. PMID: 11278366 Free article.

8

Inhibition of the mammalian target of rapamycin (mTOR) in advanced pancreatic cancer: results of two phase II studies.

Javle MM, Shroff RT, Xiong H, Varadhachary GA, Fogelman D, Reddy SA, Davis D, Zhang Y, Wolff RA, Abbruzzese JL. Javle MM, et al. Among authors: reddy sa. BMC Cancer. 2010 Jul 14;10:368. doi: 10.1186/1471-2407-10-368. BMC Cancer. 2010. PMID: 20630061 Free PMC article. Clinical Trial.

9

BSTA promotes mTORC2-mediated phosphorylation of Akt1 to suppress expression of FoxC2 and stimulate adipocyte differentiation.

Yao Y, Suraokar M, Darnay BG, Hollier BG, Shaiken TE, Asano T, Chen CH, Chang BH, Lu Y, Mills GB, Sarbassov D, Mani SA, Abbruzzese JL, Reddy SA. Yao Y, et al. Among authors: reddy sa. Sci Signal. 2013 Jan 8;6(257):ra2. doi: 10.1126/scisignal.2003295. Sci Signal. 2013. PMID: 23300339 Free PMC article.

10

Constitutive activation of AKT pathway inhibits TNF-induced apoptosis in mitochondrial DNA-deficient human myelogenous leukemia ML-1a.

Suzuki S, Naito A, Asano T, Evans TT, Reddy SA, Higuchi M. Suzuki S, et al. Among authors: reddy sa. Cancer Lett. 2008 Sep 8;268(1):31-7. doi: 10.1016/j.canlet.2008.03.020. Epub 2008 May 12. Cancer Lett. 2008. PMID: 18468786 Free PMC article.

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