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Page 1
High-throughput screening for ion channel modulators.
Falconer M, Smith F, Surah-Narwal S, Congrave G, Liu Z, Hayter P, Ciaramella G, Keighley W, Haddock P, Waldron G, Sewing A. Falconer M, et al. Among authors: keighley w. J Biomol Screen. 2002 Oct;7(5):460-5. doi: 10.1177/108705702237678. J Biomol Screen. 2002. PMID: 14599362
Measuring intracellular calcium fluxes in high throughput mode.
Chambers C, Smith F, Williams C, Marcos S, Liu ZH, Hayter P, Ciaramella G, Keighley W, Gribbon P, Sewing A. Chambers C, et al. Among authors: keighley w. Comb Chem High Throughput Screen. 2003 Jun;6(4):355-62. doi: 10.2174/138620703106298446. Comb Chem High Throughput Screen. 2003. PMID: 12769679
Evaluating real-life high-throughput screening data.
Gribbon P, Lyons R, Laflin P, Bradley J, Chambers C, Williams BS, Keighley W, Sewing A. Gribbon P, et al. Among authors: keighley w. J Biomol Screen. 2005 Mar;10(2):99-107. doi: 10.1177/1087057104271957. J Biomol Screen. 2005. PMID: 15799953
Compound management beyond efficiency.
Burr I, Winchester T, Keighley W, Sewing A. Burr I, et al. Among authors: keighley w. J Biomol Screen. 2009 Jun;14(5):485-91. doi: 10.1177/1087057109333978. Epub 2009 Jun 5. J Biomol Screen. 2009. PMID: 19502566
New working paradigms in research laboratories.
Keighley W, Sewing A. Keighley W, et al. Drug Discov Today. 2009 Jul;14(13-14):625-9. doi: 10.1016/j.drudis.2009.05.004. Epub 2009 May 27. Drug Discov Today. 2009. PMID: 19477291
Helping science to succeed: improving processes in R&D.
Sewing A, Winchester T, Carnell P, Hampton D, Keighley W. Sewing A, et al. Among authors: keighley w. Drug Discov Today. 2008 Mar;13(5-6):227-33. doi: 10.1016/j.drudis.2007.11.011. Epub 2008 Mar 5. Drug Discov Today. 2008. PMID: 18342798 Review.
Experiences in implementing uHTS--cutting edge technology meets the real world.
Gribbon P, Schaertl S, Wickenden M, Williams G, Grimley R, Stuhmeier F, Preckel H, Eggeling C, Kraemer J, Everett J, Keighley WW, Sewing A. Gribbon P, et al. Among authors: keighley ww. Curr Drug Discov Technol. 2004 Jan;1(1):27-35. doi: 10.2174/1570163043484798. Curr Drug Discov Technol. 2004. PMID: 16472217 Review.