Chen J - Search Results

1

The relative influence of metal ion binding sites in the I-like domain and the interface with the hybrid domain on rolling and firm adhesion by integrin alpha4beta7.

Chen J, Takagi J, Xie C, Xiao T, Luo BH, Springer TA. Chen J, et al. J Biol Chem. 2004 Dec 31;279(53):55556-61. doi: 10.1074/jbc.M407773200. Epub 2004 Sep 24. J Biol Chem. 2004. PMID: 15448154 Free PMC article.

2

Bistable regulation of integrin adhesiveness by a bipolar metal ion cluster.

Chen J, Salas A, Springer TA. Chen J, et al. Nat Struct Biol. 2003 Dec;10(12):995-1001. doi: 10.1038/nsb1011. Epub 2003 Nov 9. Nat Struct Biol. 2003. PMID: 14608374

3

Activation of integrin beta-subunit I-like domains by one-turn C-terminal alpha-helix deletions.

Yang W, Shimaoka M, Chen J, Springer TA. Yang W, et al. Among authors: chen j. Proc Natl Acad Sci U S A. 2004 Feb 24;101(8):2333-8. doi: 10.1073/pnas.0307291101. Proc Natl Acad Sci U S A. 2004. PMID: 14983010 Free PMC article.

4

Regulation of outside-in signaling and affinity by the beta2 I domain of integrin alphaLbeta2.

Chen J, Yang W, Kim M, Carman CV, Springer TA. Chen J, et al. Proc Natl Acad Sci U S A. 2006 Aug 29;103(35):13062-7. doi: 10.1073/pnas.0605666103. Epub 2006 Aug 18. Proc Natl Acad Sci U S A. 2006. PMID: 16920795 Free PMC article.

5

Structural specializations of α(4)β(7), an integrin that mediates rolling adhesion.

Yu Y, Zhu J, Mi LZ, Walz T, Sun H, Chen J, Springer TA. Yu Y, et al. Among authors: chen j. J Cell Biol. 2012 Jan 9;196(1):131-46. doi: 10.1083/jcb.201110023. J Cell Biol. 2012. PMID: 22232704 Free PMC article.

6

Importance of force linkage in mechanochemistry of adhesion receptors.

Astrof NS, Salas A, Shimaoka M, Chen J, Springer TA. Astrof NS, et al. Among authors: chen j. Biochemistry. 2006 Dec 19;45(50):15020-8. doi: 10.1021/bi061566o. Biochemistry. 2006. PMID: 17154539 Free PMC article.

7

Cation-pi interaction regulates ligand-binding affinity and signaling of integrin alpha4beta7.

Pan Y, Zhang K, Qi J, Yue J, Springer TA, Chen J. Pan Y, et al. Among authors: chen j. Proc Natl Acad Sci U S A. 2010 Dec 14;107(50):21388-93. doi: 10.1073/pnas.1015487107. Epub 2010 Nov 22. Proc Natl Acad Sci U S A. 2010. PMID: 21098296 Free PMC article.

8

Aberrant activation of integrin alpha4beta7 suppresses lymphocyte migration to the gut.

Park EJ, Mora JR, Carman CV, Chen J, Sasaki Y, Cheng G, von Andrian UH, Shimaoka M. Park EJ, et al. Among authors: chen j. J Clin Invest. 2007 Sep;117(9):2526-38. doi: 10.1172/JCI31570. J Clin Invest. 2007. PMID: 17786243 Free PMC article.

9

The CC' and DE loops in Ig domains 1 and 2 of MAdCAM-1 play different roles in MAdCAM-1 binding to low- and high-affinity integrin alpha4beta7.

Sun H, Wu Y, Qi J, Pan Y, Ge G, Chen J. Sun H, et al. Among authors: chen j. J Biol Chem. 2011 Apr 8;286(14):12086-92. doi: 10.1074/jbc.M110.208900. Epub 2011 Feb 4. J Biol Chem. 2011. PMID: 21296888 Free PMC article.

10

The unique disulfide bond-stabilized W1 β4-β1 loop in the α4 β-propeller domain regulates integrin α4β7 affinity and signaling.

Yue J, Pan Y, Sun L, Zhang K, Liu J, Lu L, Chen J. Yue J, et al. Among authors: chen j. J Biol Chem. 2013 May 17;288(20):14228-14237. doi: 10.1074/jbc.M113.462630. Epub 2013 Apr 3. J Biol Chem. 2013. PMID: 23553626 Free PMC article.

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