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A single administration of recombinant human interleukin-12 is associated with increased expression levels of interferon-gamma and signal transducer and activator of transcription in healthy subjects.
Trudeau C, Cotreau MM, Stonis L, Dykstra KH, Oestreicher JL, Strahs A, Dorner AJ, Van Cleave VH, Trepicchio WL, Schwertschlag US. Trudeau C, et al. Among authors: schwertschlag us. J Clin Pharmacol. 2005 Jun;45(6):649-58. doi: 10.1177/0091270005276116. J Clin Pharmacol. 2005. PMID: 15901746
Anti-interleukin-12 antibody for active Crohn's disease.
Mannon PJ, Fuss IJ, Mayer L, Elson CO, Sandborn WJ, Present D, Dolin B, Goodman N, Groden C, Hornung RL, Quezado M, Yang Z, Neurath MF, Salfeld J, Veldman GM, Schwertschlag U, Strober W; Anti-IL-12 Crohn's Disease Study Group. Mannon PJ, et al. N Engl J Med. 2004 Nov 11;351(20):2069-79. doi: 10.1056/NEJMoa033402. N Engl J Med. 2004. PMID: 15537905 Free article. Clinical Trial.
17 results