Kangasniemi L - Search Results

1

Noninvasive dual modality in vivo monitoring of the persistence and potency of a tumor targeted conditionally replicating adenovirus.

Kanerva A, Zinn KR, Peng KW, Ranki T, Kangasniemi L, Chaudhuri TR, Desmond RA, Wang M, Takayama K, Hakkarainen T, Alfthan H, Stenman UH, Curiel DT, Hemminki A. Kanerva A, et al. Among authors: kangasniemi l. Gene Ther. 2005 Jan;12(1):87-94. doi: 10.1038/sj.gt.3302387. Gene Ther. 2005. PMID: 15385953

2

Verapamil results in increased blood levels of oncolytic adenovirus in treatment of patients with advanced cancer.

Koski A, Raki M, Nokisalmi P, Liikanen I, Kangasniemi L, Joensuu T, Kanerva A, Pesonen S, Alemany R, Hemminki A. Koski A, et al. Among authors: kangasniemi l. Mol Ther. 2012 Jan;20(1):221-9. doi: 10.1038/mt.2011.230. Epub 2011 Nov 1. Mol Ther. 2012. PMID: 22044933 Free PMC article.

3

Combination of gemcitabine and Ad5/3-Delta24, a tropism modified conditionally replicating adenovirus, for the treatment of ovarian cancer.

Raki M, Kanerva A, Ristimaki A, Desmond RA, Chen DT, Ranki T, Sarkioja M, Kangasniemi L, Hemminki A. Raki M, et al. Among authors: kangasniemi l. Gene Ther. 2005 Aug;12(15):1198-205. doi: 10.1038/sj.gt.3302517. Gene Ther. 2005. PMID: 15800658

4

A heparan sulfate-targeted conditionally replicative adenovirus, Ad5.pk7-Delta24, for the treatment of advanced breast cancer.

Ranki T, Kanerva A, Ristimäki A, Hakkarainen T, Särkioja M, Kangasniemi L, Raki M, Laakkonen P, Goodison S, Hemminki A. Ranki T, et al. Among authors: kangasniemi l. Gene Ther. 2007 Jan;14(1):58-67. doi: 10.1038/sj.gt.3302830. Epub 2006 Aug 10. Gene Ther. 2007. PMID: 16900223 Free PMC article.

5

Extended release of adenovirus from silica implants in vitro and in vivo.

Kangasniemi L, Koskinen M, Jokinen M, Toriseva M, Ala-Aho R, Kähäri VM, Jalonen H, Ylä-Herttuala S, Moilanen H, Stenman UH, Diaconu I, Kanerva A, Pesonen S, Hakkarainen T, Hemminki A. Kangasniemi L, et al. Gene Ther. 2009 Jan;16(1):103-10. doi: 10.1038/gt.2008.142. Epub 2008 Aug 28. Gene Ther. 2009. PMID: 18754041

6

Infectivity-enhanced adenoviruses deliver efficacy in clinical samples and orthotopic models of disseminated gastric cancer.

Kangasniemi L, Kiviluoto T, Kanerva A, Raki M, Ranki T, Sarkioja M, Wu H, Marini F, Höckerstedt K, Isoniemi H, Alfthan H, Stenman UH, Curiel DT, Hemminki A. Kangasniemi L, et al. Clin Cancer Res. 2006 May 15;12(10):3137-44. doi: 10.1158/1078-0432.CCR-05-2576. Clin Cancer Res. 2006. PMID: 16707613

7

Noninvasive imaging for evaluation of the systemic delivery of capsid-modified adenoviruses in an orthotopic model of advanced lung cancer.

Sarkioja M, Kanerva A, Salo J, Kangasniemi L, Eriksson M, Raki M, Ranki T, Hakkarainen T, Hemminki A. Sarkioja M, et al. Among authors: kangasniemi l. Cancer. 2006 Oct 1;107(7):1578-88. doi: 10.1002/cncr.22209. Cancer. 2006. PMID: 16948124 Free article.

8

Treatment of prostate cancer with Ad5/3Delta24hCG allows non-invasive detection of the magnitude and persistence of virus replication in vivo.

Rajecki M, Kanerva A, Stenman UH, Tenhunen M, Kangasniemi L, Särkioja M, Ala-Opas MY, Alfthan H, Sankila A, Rintala E, Desmond RA, Hakkarainen T, Hemminki A. Rajecki M, et al. Among authors: kangasniemi l. Mol Cancer Ther. 2007 Feb;6(2):742-51. doi: 10.1158/1535-7163.MCT-06-0403. Mol Cancer Ther. 2007. PMID: 17308070

9

Systemic therapy for cervical cancer with potentially regulatable oncolytic adenoviruses.

Kanerva A, Lavilla-Alonso S, Raki M, Kangasniemi L, Bauerschmitz GJ, Takayama K, Ristimäki A, Desmond RA, Hemminki A. Kanerva A, et al. Among authors: kangasniemi l. PLoS One. 2008 Aug 13;3(8):e2917. doi: 10.1371/journal.pone.0002917. PLoS One. 2008. PMID: 18698374 Free PMC article.

10

Treatment of cancer patients with a serotype 5/3 chimeric oncolytic adenovirus expressing GMCSF.

Koski A, Kangasniemi L, Escutenaire S, Pesonen S, Cerullo V, Diaconu I, Nokisalmi P, Raki M, Rajecki M, Guse K, Ranki T, Oksanen M, Holm SL, Haavisto E, Karioja-Kallio A, Laasonen L, Partanen K, Ugolini M, Helminen A, Karli E, Hannuksela P, Pesonen S, Joensuu T, Kanerva A, Hemminki A. Koski A, et al. Among authors: kangasniemi l. Mol Ther. 2010 Oct;18(10):1874-84. doi: 10.1038/mt.2010.161. Epub 2010 Jul 27. Mol Ther. 2010. PMID: 20664527 Free PMC article. Clinical Trial.

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