Silva A - Search Results

1

Activation of PI3K is indispensable for interleukin 7-mediated viability, proliferation, glucose use, and growth of T cell acute lymphoblastic leukemia cells.

Barata JT, Silva A, Brandao JG, Nadler LM, Cardoso AA, Boussiotis VA. Barata JT, et al. Among authors: silva a. J Exp Med. 2004 Sep 6;200(5):659-69. doi: 10.1084/jem.20040789. J Exp Med. 2004. PMID: 15353558 Free PMC article.

2

Molecular and functional evidence for activity of murine IL-7 on human lymphocytes.

Barata JT, Silva A, Abecasis M, Carlesso N, Cumano A, Cardoso AA. Barata JT, et al. Among authors: silva a. Exp Hematol. 2006 Sep;34(9):1133-42. doi: 10.1016/j.exphem.2006.05.001. Exp Hematol. 2006. PMID: 16939806 Free article.

3

PTEN posttranslational inactivation and hyperactivation of the PI3K/Akt pathway sustain primary T cell leukemia viability.

Silva A, Yunes JA, Cardoso BA, Martins LR, Jotta PY, Abecasis M, Nowill AE, Leslie NR, Cardoso AA, Barata JT. Silva A, et al. J Clin Invest. 2008 Nov;118(11):3762-74. doi: 10.1172/JCI34616. Epub 2008 Oct 1. J Clin Invest. 2008. PMID: 18830414 Free PMC article.

4

IL-7 contributes to the progression of human T-cell acute lymphoblastic leukemias.

Silva A, Laranjeira AB, Martins LR, Cardoso BA, Demengeot J, Yunes JA, Seddon B, Barata JT. Silva A, et al. Cancer Res. 2011 Jul 15;71(14):4780-9. doi: 10.1158/0008-5472.CAN-10-3606. Epub 2011 May 18. Cancer Res. 2011. PMID: 21593192

5

STAT5 is essential for IL-7-mediated viability, growth, and proliferation of T-cell acute lymphoblastic leukemia cells.

Ribeiro D, Melão A, van Boxtel R, Santos CI, Silva A, Silva MC, Cardoso BA, Coffer PJ, Barata JT. Ribeiro D, et al. Among authors: silva a, silva mc. Blood Adv. 2018 Sep 11;2(17):2199-2213. doi: 10.1182/bloodadvances.2018021063. Blood Adv. 2018. PMID: 30185437 Free PMC article.

6

Intracellular reactive oxygen species are essential for PI3K/Akt/mTOR-dependent IL-7-mediated viability of T-cell acute lymphoblastic leukemia cells.

Silva A, Gírio A, Cebola I, Santos CI, Antunes F, Barata JT. Silva A, et al. Leukemia. 2011 Jun;25(6):960-7. doi: 10.1038/leu.2011.56. Epub 2011 Apr 1. Leukemia. 2011. PMID: 21455214

7

Common gamma chain-signaling cytokines promote proliferation of T-cell acute lymphoblastic leukemia.

Barata JT, Keenan TD, Silva A, Nadler LM, Boussiotis VA, Cardoso AA. Barata JT, et al. Among authors: silva a. Haematologica. 2004 Dec;89(12):1459-67. Haematologica. 2004. PMID: 15590396

8

Regulation of PTEN by CK2 and Notch1 in primary T-cell acute lymphoblastic leukemia: rationale for combined use of CK2- and gamma-secretase inhibitors.

Silva A, Jotta PY, Silveira AB, Ribeiro D, Brandalise SR, Yunes JA, Barata JT. Silva A, et al. Haematologica. 2010 Apr;95(4):674-8. doi: 10.3324/haematol.2009.011999. Epub 2009 Dec 16. Haematologica. 2010. PMID: 20015880 Free PMC article.

9

Overexpression of wild-type IL-7Rα promotes T-cell acute lymphoblastic leukemia/lymphoma.

Silva A, Almeida ARM, Cachucho A, Neto JL, Demeyer S, de Matos M, Hogan T, Li Y, Meijerink J, Cools J, Grosso AR, Seddon B, Barata JT. Silva A, et al. Blood. 2021 Sep 23;138(12):1040-1052. doi: 10.1182/blood.2019000553. Blood. 2021. PMID: 33970999 Free PMC article.

10

Aberrant signaling in T-cell acute lymphoblastic leukemia: biological and therapeutic implications.

Cardoso BA, Gírio A, Henriques C, Martins LR, Santos C, Silva A, Barata JT. Cardoso BA, et al. Among authors: silva a. Braz J Med Biol Res. 2008 May;41(5):344-50. doi: 10.1590/s0100-879x2008005000016. Epub 2008 Apr 30. Braz J Med Biol Res. 2008. PMID: 18488097 Free article. Review.

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